Results 71 to 80 of about 740,184 (342)

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang   +10 more
wiley   +1 more source

Mathematics and medicine. Test reduction: III-Practical applications. [PDF]

open access: yesBMJ, 1980
While there is no generally applicable method of test reduction, ways in which the problem can be tackled can usually be suggested. These include the examination of error rates of tests and the use of current statistical methods. When the cost-effectiveness of some more expensive test has to be measured, a model of the decision problem needs to be ...
W I, Card, P A, Emerson
openaire   +2 more sources

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz   +9 more
wiley   +1 more source

Predicting the impact of placing an overdose prevention site in Philadelphia: a mathematical modeling approach

open access: yesHarm Reduction Journal, 2021
Background Fatal overdoses from opioid use and substance disorders are increasing at an alarming rate. One proposed harm reduction strategy for reducing overdose fatalities is to place overdose prevention sites—commonly known as safe injection facilities—
Joanna R. Wares   +6 more
doaj   +1 more source

Removing opportunities to calculate improves students' performance on subsequent word problems. [PDF]

open access: yes, 2019
BackgroundIn two studies we investigated whether removing opportunities to calculate could improve students' subsequent ability to solve similar word problems.
Givvin, Karen B   +3 more
core  

Reduction of flexible joint manipulator mathematical model

open access: yesCollection of selected papers of the III International Conference on Information Technology and Nanotechnology, 2017
The singularly perturbed differential systems which describe the dynamics of the manipulator with flexible joints are investigated under the condition of weak dissipation. The method of integral manifolds is used to construct the reduced model of robot. Integral manifolds may be constructed as an asymptotic power series. The simplified model is used to
Olga V. Vidilina, Natalya V. Voropaeva
openaire   +1 more source

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

open access: yesInternational Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam   +2 more
wiley   +1 more source

A Mathematical Model of the Alumina Reduction Cell

open access: yesECS Proceedings Volumes, 1975
Abstract Based upon the equations of irreversible thermodynamics, and assuming local equilibrium, expressions are developed for the current efficiency, anode gas composition and voltage for the production of aluminum by the electrolytic process.A fundamental assumption of the model is that the electrolyte is a partial electronic conductor by virtue of ...
openaire   +1 more source

Mathematical reduction of a heart dipole model

open access: yesJournal of Computational and Applied Mathematics, 1989
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Morgan, Alexander P.   +2 more
openaire   +2 more sources

A Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
Block Diagram of the Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller. ABSTRACT This article introduces a discrete‐time robust adaptive one‐sample‐ahead preview super‐twisting sliding mode controller. A stability analysis of the controller by Lyapunov criteria is developed to demonstrate its robustness in handling both ...
Guilherme Vieira Hollweg   +5 more
wiley   +1 more source

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