Results 151 to 160 of about 781,120 (260)

A reference genome sequence for the exceptionally long-lived Great Basin bristlecone pine, Pinus longaeva. [PDF]

G3 (Bethesda)
Neale DB, Zimin AV, Millar CI, McGuire PE, Hosea JA, Li E, Puiu D, Timp W, Salzberg SL.   +8 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

The reference genome of the Asian Elephant (Elephas maximus): a foundation for conservation and genomic research. [PDF]

BMC Genomics
De Panis D, Arantes LS, Brown T, Somenzi E, Wibbelt G, Ballaco J, Mountcastle J, Brajuka N, Joardar VS, Fedrigo O, Thibaud-Nissen F, Ryder OA, Jarvis E, Lummaa V, Mazzoni CJ.   +14 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A chromosome-level reference genome for Pacific herring (<i>Clupea pallasii)</i> from the Bering Sea. [PDF]

GigaByte
Timm LE, Hsieh YC, López JA, Almgren SA, Glass JR.   +4 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

A chromosome-level reference genome assembly for Gilbert's skink Plestiodon gilberti. [PDF]

J Hered
Richmond JQ, Escalona M, Marimuthu MPA, Nguyen O, Sacco S, Beraut E, Toffelmier E, Karin BR, Cooper RD, Fisher RN, Wang IJ, Shaffer HB.   +11 more
europepmc   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Reference genome of the leopard seal (Hydrurga leptonyx), a Southern Ocean apex predator

Frontiers in Genetics
J. Canitz, S. S. Kienle, S. S. Kienle, K. van der Linde, R. Borras-Chavez, R. Borras-Chavez, E. S. Sperou, A. Leahy, A. Leahy, S. Rivera, S. Rivera, M. Autenrieth, J. I. Hoffman, J. I. Hoffman, J. I. Hoffman, J. I. Hoffman, J. I. Hoffman, C. A. Bonin   +17 more
doaj   +1 more source

MarpolBase: genome database for Marchantia polymorpha featuring high quality reference genome sequences. [PDF]

Plant Cell Physiol
Tanizawa Y, Mochizuki T, Yagura M, Sakamoto M, Fujisawa T, Kawamura S, Shimokawa E, Yamaoka S, Nishihama R, Bowman JL, Berger F, Yamato KT, Kohchi T, Nakamura Y.   +13 more
europepmc   +1 more source