Results 11 to 20 of about 781,120 (260)
The era of reference genomes in conservation genomics [PDF]
Trends in Ecology & Evolution, 2022 Trends in Ecology & Evolution, 37 (3)
Formenti, Giulio +157 more
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Modernizing reference genome assemblies. [PDF]
PLoS Biology, 2011 I have read the journal's policy and have the following conflicts: Paul Flicek is married to the deputy editor of PLoS Medicine, Melissa Norton. Evan Eichler is on the board of Pacific Biosciences. Support for this work came from the Intramural Research Program of the NIH, The National Library of Medicine, the European Molecular Biology ...
Deanna M Church +38 more
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Reference based genome compression [PDF]
2012 IEEE Information Theory Workshop, 2012 DNA sequencing technology has advanced to a point where storage is becoming the central bottleneck in the acquisition and mining of more data. Large amounts of data are vital for genomics research, and generic compression tools, while viable, cannot offer the same savings as approaches tuned to inherent biological properties. We propose an algorithm to
Bobbie Chern +5 more
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The value of new genome references [PDF]
Experimental Cell Research, 2017 Genomic information has become a ubiquitous and almost essential aspect of biological research. Over the last 10-15 years, the cost of generating sequence data from DNA or RNA samples has dramatically declined and our ability to interpret those data increased just as remarkably.
Kim C, Worley +2 more
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The genome atlas: navigating a new era of reference genomes [PDF]
Trends in Genetics, 2021 The reference genome serves two distinct purposes within the field of genomics. First, it provides a persistent structure against which findings can be reported, allowing for universal knowledge exchange between users. Second, it reduces the computational costs and time required to process genomic data by creating a scaffold that can be relied upon by ...
Alice M, Kaye, Wyeth W, Wasserman
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One reference genome is not enough [PDF]
Genome Biology, 2019 A recent study on human structural variation indicates insufficiencies and errors in the human reference genome, GRCh38, and argues for the construction of a human pan-genome.
Yang, Xiaofei +3 more
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Benchmark study for evaluating the quality of reference genomes and gene annotations in 114 species
Frontiers in Veterinary Science, 2023 IntroductionFor reference genomes and gene annotations are key materials that can determine the limits of the molecular biology research of a species; however, systematic research on their quality assessment remains insufficient.MethodsWe collected ...
Sinwoo Park +7 more
doaj +1 more source
Frontiers in Plant Science, 2021 Genes have been lost or weakened from cultivated rice during rice domestication and breeding. Weedy rice (Oryza sativa f. spontanea) is usually recognized as the progeny between cultivated rice and wild rice and is also known to harbor an gene pool for ...
Fei Li +19 more
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Genomic surveillance of methicillin-resistant Staphylococcus aureus in the Philippines, 2013–2014
Western Pacific Surveillance and Response, 2021 Methicillin-resistant Staphylococcus aureus (MRSA) remains one of the leading causes of both nosocomial and community infections worldwide. In the Philippines, MRSA rates have remained above 50% since 2010, but resistance to other antibiotics, including ...
Melissa L. Masim +15 more
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Genomic surveillance of Pseudomonas aeruginosa in the Philippines, 2013-2014
Western Pacific Surveillance and Response, 2021 Pseudomonas aeruginosa is an opportunistic pathogen that often causes nosocomial infections resistant to treatment. Rates of antimicrobial resistance (AMR) are increasing, as are rates of multidrug-resistant (MDR) and possible extensively drug-resistant (
Jeremiah Chilam +16 more
doaj +1 more source