Results 111 to 120 of about 12,282,811 (238)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

The standard for portfolio management

, 2017
The Standard for Portfolio Management – Fourth Edition has been updated to best reflect the current state of portfolio management. It describe the principles that drive accepted good portfolio management practices in today’s organizations.
Project Management Institute, Project Institute   +1 more
core  

Boston University School of Management faculty profiles [PDF]

, 1991
Profiles of Boston University School of Management faculty (1991/1992)
Boston University School of Management
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Predictive Efficacy of Dual Therapies Combining Integrase Strand Transfer Inhibitors with Second-Generation Non-Nucleoside Reverse Transcriptase Inhibitors Following HIV-1 Treatment Failure in Cameroon: Implications for the Use of a Long-Acting Therapeutic Strategy in Low- and Middle-Income Countries

Viruses
Dual therapies (DT) combining integrase strand transfer inhibitors (INSTIs) with second-generation non-nucleoside reverse transcriptase inhibitors (2nd-Gen-NNRTIs) offer new possibilities for HIV treatment to improve adherence.
Davy-Hyacinthe Gouissi Anguechia, Yagai Bouba, Ezechiel Ngoufack Jagni Semengue, Aude Christelle Ka’e, Désiré Takou, Collins Ambe Chenwi, Grace Beloumou, Alex Durand Nka, Ulrich Roland Basseck Wome, Maria Mercedes Santoro, Francesca Ceccherini-Silberstein, Adawaye Chatté, Carla Montesano, Giulia Cappelli, Vittorio Colizzi, Alexis Ndjolo, Dora Mbanya, Nicaise Ndembi, Carlo-Federico Perno, Joseph Fokam   +19 more
doaj   +1 more source

The standard for organizational project management (OPM)

, 2018
The Standard for Organizational Project Management (OPM) provides a framework and integrated approach using portfolio, program, and project management to deliver organizational strategy for better performance, better results, and a sustainable ...
Project Management Institute
core  

Boston University School of Management faculty profiles [PDF]

, 1992
Profiles of Boston University School of Management faculty (1992/1993)
Boston University School of Management
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Empowering adolescents living with perinatally-acquired HIV: tailored CD4+ count assessment for optimized care, the EDCTP READY-study

Frontiers in Medicine
BackgroundThe elevated rate of AIDS-related mortality in Sub-Saharan Africa among adolescents living with HIV (ALHIV) is influenced by various factors, notably immunosuppression, within a framework of limited therapeutic alternatives. We aimed to enhance
Willy Le Roi Togna Pabo, Willy Le Roi Togna Pabo, Willy Le Roi Togna Pabo, Aurelie Minelle Kengni Ngueko, Aurelie Minelle Kengni Ngueko, Alex Durand Nka, Alex Durand Nka, Alex Durand Nka, Maria Mercedes Santoro, Yagai Bouba, Yagai Bouba, Collins Ambe Chenwi, Ezéchiel Ngoufack Jagni Semengue, Ezéchiel Ngoufack Jagni Semengue, Ezéchiel Ngoufack Jagni Semengue, Désiré Takou, Georges Teto, Beatrice Dambaya, Raymond Babila Nyasa, Michel Carlos Tommo Tchouaket, Michel Carlos Tommo Tchouaket, Grace Angong Beloumou, Sandrine Claire Djupsa Ndjeyep, Aude Christelle Ka’e, Tatiana Anim Keng Tekoh, Derrick Tambe Ayuk Ngwese, Naomi-Karell Etame, Rachel Audrey Nayang Mundo, Rachel Simo Kamgaing, Samuel Martin Sosso, Roland Ndip Ndip, Vittorio Colizzi, Vittorio Colizzi, Vittorio Colizzi, Francesca Cecchereni-Silberstein, Alexis Ndjolo, Joseph Fokam, Joseph Fokam, Joseph Fokam, Joseph Fokam, Joseph Fokam   +40 more
doaj   +1 more source

Reference Management [PDF]

, 2013
Martin Fenner, Kaja Scheliga, Sönke Bartling   +2 more
openaire   +1 more source