Results 121 to 130 of about 12,282,811 (238)

Requirements management: a practice guide

open access: yes, 2016
Organizations continue to experience project issues associated with poor performance on requirements-related activities. This guide will give you the tools you need to excel in requirements development and management — components of the larger field of ...
Project Management Institute   +1 more
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Predicting and Recognizing Drug‐Induced Type I Brugada Pattern Using ECG‐Based Deep Learning

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Brugada syndrome (BrS) has been associated with sudden cardiac death in otherwise healthy subjects, and drug‐induced BrS accounts for 55% to 70% of all patients with BrS.
Paul‐Adrian Călburean   +19 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Electroanatomic mapping reconstruction with photogrammetry across different mapping systems

open access: yesFrontiers in Imaging
BackgroundAutomatic digital photogrammetry produces digital reproductions of objects using photographs. The aim of this study is to analyze feasibility of photogrammetry for electroanatomic map (EAM) reconstruction from different mapping systems ...
Giacomo Talevi   +15 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Health and Medical Reference Guidelines 2015 Retired

open access: yes, 2015
These guidelines are for all information services staff (hereafter referred to as “staff”), regardless ofquestions or library type. Health and Medical Reference refers to questions that pertain to any aspect ofhealth, medicine, or biomedicine, including ...
Reference Services Section (RSS) Executive Committee
core  

Effects of Interpersonal Trust on Employee Avoidance and Approach Self-regulation

open access: yes, 2009
Academy of Management 2009 Annual Meeting: Green Management Matters, AOM ...
DANIEL J. MCALLISTER   +8 more
core   +1 more source

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