Results 101 to 110 of about 2,154,603 (302)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Fixed points and self‐reference [PDF]
It is shown how Gödel′s famous diagonal argument and a generalization of the recursion theorem are derivable from a common construation. The abstract fixed point theorem of this article is independent of both metamathematics and recursion theory and is perfectly comprehensible to the non‐specialist.
openaire +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Il National Reference Point Italiano
Il National Reference Point Italiano ha sostenuto l’attuazione della Raccomandazione europea sulla garanzia di qualità dell’istruzione e formazione professionale ed il processo nazionale di definizione di un approccio all’assicurazione di qualità ...
Evangelista, Laura
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A Revealed Reference Point for Prospect Theory [PDF]
Without an instrument to identify the reference point, prospect theory includes a degree of freedom that makes the model difficult to falsify. To address this issue, we propose a foundation for prospect theory that advances existing approaches with three
Zank, Horst; id_orcid +5 more
core +1 more source
An extension of the MOORA method for solving fuzzy decision making problems
The aim of this paper is to propose an extension of the MOORA method to use the triangular fuzzy numbers. In this paper, several methods for defuzzification and calculation of the distance between two fuzzy numbers, are discussed.
Dragisa Stanujkic
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Prescriptive Norms and Social Comparisons
This paper analyzes the equilibrium strength of prescriptive norms to contribute to public goods. We consider three methods of establishing what an acceptable contribution to the public good is.
Moti Michaeli, Daniel Spiro
doaj +1 more source

