Results 101 to 110 of about 2,154,603 (302)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Fixed points and self‐reference [PDF]

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1984
It is shown how Gödel′s famous diagonal argument and a generalization of the recursion theorem are derivable from a common construation. The abstract fixed point theorem of this article is independent of both metamathematics and recursion theory and is perfectly comprehensible to the non‐specialist.
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Il National Reference Point Italiano

open access: yes, 2022
Il National Reference Point Italiano ha sostenuto l’attuazione della Raccomandazione europea sulla garanzia di qualità dell’istruzione e formazione professionale ed il processo nazionale di definizione di un approccio all’assicurazione di qualità ...
Evangelista, Laura
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Revealed Reference Point for Prospect Theory [PDF]

open access: yes, 2018
Without an instrument to identify the reference point, prospect theory includes a degree of freedom that makes the model difficult to falsify. To address this issue, we propose a foundation for prospect theory that advances existing approaches with three
Zank, Horst; id_orcid   +5 more
core   +1 more source

An extension of the MOORA method for solving fuzzy decision making problems

open access: yesTechnological and Economic Development of Economy, 2014
The aim of this paper is to propose an extension of the MOORA method to use the triangular fuzzy numbers. In this paper, several methods for defuzzification and calculation of the distance between two fuzzy numbers, are discussed.
Dragisa Stanujkic
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Prescriptive Norms and Social Comparisons

open access: yesGames, 2018
This paper analyzes the equilibrium strength of prescriptive norms to contribute to public goods. We consider three methods of establishing what an acceptable contribution to the public good is.
Moti Michaeli, Daniel Spiro
doaj   +1 more source

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