A Reference Point-Based Evolutionary Algorithm Solves Multi and Many-Objective Optimization Problems: Method and Validation. [PDF]
Jameel M, Abouhawwash M.
europepmc +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
As a metaheuristic method for the continuous optimization problem, the grey wolf optimizer (GWO) has attracted much attention from researchers because the method is reported to be superior to other methods.
Keiji Tatsumi, Nao Kinoshita
doaj +1 more source
Integrating prospect theory with variable reference point into the conversion-based framework for linear ordinal ranking aggregation. [PDF]
Liu N, Xu Z, Wu H, Ren P.
europepmc +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Antilingula as a Surgical Reference Point for Vertical Ramus Osteotomy. [PDF]
Chen HS, Chen YS, Lin IL, Chen CF.
europepmc +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Identical External Reference Point Standardized to the Zero-Reference Level for Measuring Both Central and Jugular Venous Pressures: An Observational Study. [PDF]
Karmacharya N, Bhattarai MD, Pradhan A.
europepmc +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Numerical Feedback Roundness Affects the Choice of the Self vs. Others as a Reference Point. [PDF]
Shoham M, Munichor N.
europepmc +1 more source

