Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Distances to a Point of Reference in Spatial Point Patterns
, 2014 Motivated by a study of social spider behavior, we discuss the distribution of the distances from all the events in a spatial point pattern to a point of reference that has a known location at a given moment of time.
Joyner, Michele L. +2 more
core +1 more source
A Circular-Based Reference Point Extraction Method for Correcting the Alignment of Round Parts. [PDF]
Sensors (Basel), 2022 Moon CB, Kim BM, Kim DS.
europepmc +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Emotional) Reference Point Formation
, 2016 Decision-makers code financial outcomes as gains or losses relative to a reference point but little research has considered what influences its formation. Using an eye-tracking experiment, we show that incidental emotions impact reference point formation
Joseph Johnson +2 more
core
A Reference Point-Based Evolutionary Algorithm Solves Multi and Many-Objective Optimization Problems: Method and Validation. [PDF]
Comput Intell Neurosci, 2023 Jameel M, Abouhawwash M.
europepmc +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Integrating prospect theory with variable reference point into the conversion-based framework for linear ordinal ranking aggregation. [PDF]
Soft comput, 2022 Liu N, Xu Z, Wu H, Ren P.
europepmc +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Antilingula as a Surgical Reference Point for Vertical Ramus Osteotomy. [PDF]
Biomed Res Int, 2021 Chen HS, Chen YS, Lin IL, Chen CF.
europepmc +1 more source