Results 91 to 100 of about 112,532 (287)
Smart Nanostructures and Synthetic Quantum Systems [PDF]
, 2001 So far proposed quantum computers use fragile and environmentally sensitive natural quantum systems. Here we explore the notion that synthetic quantum systems suitable for quantum computation may be fabricated from smart nanostructures using topological ...
Cahill, Reginald T.
core +3 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
The Speech Act of Naming in Fictional Discourse
Studia Semiotyczne, 2022 DOI: https://doi.org/10.26333/sts.xxxvi1.08 This paper argues that García-Carpintero’s theory of proper names (the Mill-Frege theory) and his theory of fiction-making do not work well together.
Amalia Haro Marchal
doaj
Où est "ailleurs" ? Sémantique lexicale de l'adverbe spatial "ailleurs".
Corela, 2013 Like other words, we think that the French spatial adverbial ailleurs contains two kinds of information: a conceptual meaning and a procedural meaning that depends on the semantico-referential process it involves. This article postulates that ailleurs is
Marie Lammert
doaj +1 more source
Specificity and definiteness in sentence and discourse structure [PDF]
, 2013 In this paper, I argue that this informally given list of characteristics covers only a certain subclass of specific indefinites. […] In particular, I dispute the definition of specific indefinites as "the speaker has the referent in mind" as rather ...
Heusinger, Klaus von
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
A comparison of addressee detection methods for multiparty conversations [PDF]
, 2009 Several algorithms have recently been proposed for recognizing addressees in a group conversational setting. These algorithms can rely on a variety of factors including previous conversational roles, gaze and type of dialogue act.
Akker, Rieks op den, Traum, David
core +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source