Results 91 to 100 of about 58,106,883 (320)
Query Modification in Object-oriented Database Federation [PDF]
, 1997 We discuss the modification of queries against an integrated view in a federation of object-oriented databases. We present a generalisation of existing algorithms for simple global query processing that works for arbitrarily defined integration classes ...
Apers, Peter M.G., Vermeer, Mark W.W.
core +5 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Survival processing versus self-reference : a memory advantage following descriptive self-referential encoding [PDF]
, 2017 Previous research has shown that rating words for their relevance to a survival scenario leads to better retention of the words than rating them for self-reference. Past studies have, however, relied exclusively on an autobiographical self-reference task
Anderson, Rachel J. +3 more
core +2 more sources
Adaptive Fault Diagnosis using Self-Referential Reasoning [PDF]
, 2017 This article will appear in a book on Self-Referential Reasoning dedicated to Raymond ...
openaire +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
“Definite Associative Deixis”: Between Referential and Attributive Readings
DiscoursThis paper investigates different readings of definite descriptions within “definite associative deixis”. The term itself was proposed in Dvořák (2023) to refer to Hawkins’ “larger situation uses based on general knowledge” (1978).
Jan Dvořák
doaj +1 more source
, 2017 The Knower paradox purports to place surprising a priori limitations on what we can know. According to orthodoxy, it shows that we need to abandon one of three plausible and widely-held ideas: that knowledge is factive, that we can know that knowledge is
Jerzak, Ethan
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source