Results 111 to 120 of about 58,106,883 (320)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Typological parameters of genericity [PDF]
, 2000 Different languages employ different morphosyntactic devices for expressing genericity. And, of course, they also make use of different morphosyntactic and semantic or pragmatic cues which may contribute to the interpretation of a sentence as generic ...
Behrens, Leila
core
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Vocal Resonances and Sound Memory in Helen Brown
Revista Brasileira de Estudos da Presença, 2016 The paper focuses on aspects related to the intensification of the uses of the voice and the musical sonority proposed by Trinidad Piriz and Daniel Marabolí on Helen Brown (2013).
Andrés Grumann Sölter (Pontificia Universidad Católica de Chile – Santiago, Chile)
doaj +2 more sources
, 2010 A standard view of reference holds that a speaker's use of a name refers to a certain thing in virtue of the speaker's associating a condition with that use that singles the referent out.
deRosset, Louis
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
ANALYSIS OF MINING ORE CONCENTRATES WITH A LOW COST PORTABLE LIBS SYSTEM
Investigación & Desarrollo, 2018 Identifying minerals in ore concentrates require costly techniques and preparation of samples, thus limiting their instant analysis. We present the development of a low-cost portable LIBS (Laser Induced Breakdown Spectroscopy) system, to identify atomic ...
Omar Ormachea +2 more
doaj
A tracker alignment framework for augmented reality [PDF]
, 2003 To achieve accurate registration, the transformations which locate the tracking system components with respect to the environment must be known. These transformations relate the base of the tracking system to the virtual world and the tracking system's ...
Baillot, Y. +3 more
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source