RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
REFERENTIATION OPERATION AND LITERACY: THE USE OF PREFABS
Matraga, 2015 This paper presents a socio-cognitive approach of the referentiation process, in order to check to what extent and in which way the strategies adopted in the treatment of the lexicon in the literacy process can be updated, or even confirmed, in reading or in writing.
openaire +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Rethinking the Origins of Cross-Language Effects: How Heard Verbs Influence Japanese- and English-Speaking Children's Attention to the Details of Actions. [PDF]
Dev SciHagihara H +3 more
europepmc +1 more source
The Use of Referential Constraints in Structuring Discourse
, 2002 The quality of discourse structure annotations is negatively influenced by the numerous difficulties that occur in the analysis process. In contrast, referential annotation resources are considerably more reliable, given the high precision of the existent anaphora resolution systems.
Seretan, Violeta, Dan, Cristea
openaire +1 more source
The Attributive/Referential Distinction, Pragmatics, Modularity of Mind and Modularization
, 2011 A. Capone
semanticscholar +1 more source
Optimizing Referential Coherence in Text Generation
International Conference on Computational Logic, 2004 R. Kibble, R. Power
semanticscholar +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Tokenization techniques for privacy-preserving healthcare data: tokenization nuts and bolts. [PDF]
Front Drug Saf RegulCook CV.
europepmc +1 more source