Results 61 to 70 of about 5,722 (246)
European Journal of American Studies, 2010 The essay examines Donald Barthelme’s Snow White’s from the perspective of the ethical philosophy of Emmanuel Levinas. Drawing on a reciprocity between Barthelme’s collage principle and Levinas’s notion of the there is, the paper applies the concept in ...
Zuzanna Ładyga
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Who Is to Believe When You Bet: on Non-Referential Indexical Functions of the Pronoun You in English
Cultura, Lenguaje y Representación, 2014 Using English-language material this paper presents an account of a number of functions of the pronoun you that are not directly related to reference. The analysis focuses on occurrences of the second-person pronoun in utterances of prediction, judgment
Katherine Hrisonopulo
doaj
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
The Speech Act of Naming in Fictional Discourse
Studia Semiotyczne, 2022 DOI: https://doi.org/10.26333/sts.xxxvi1.08 This paper argues that García-Carpintero’s theory of proper names (the Mill-Frege theory) and his theory of fiction-making do not work well together.
Amalia Haro Marchal
doaj
Où est "ailleurs" ? Sémantique lexicale de l'adverbe spatial "ailleurs".
Corela, 2013 Like other words, we think that the French spatial adverbial ailleurs contains two kinds of information: a conceptual meaning and a procedural meaning that depends on the semantico-referential process it involves. This article postulates that ailleurs is
Marie Lammert
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source