Results 51 to 60 of about 553,328 (316)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

What must not be named

EMBO Reports
Scientists working with animals must maintain a delicate balance between conducting high-quality science and legal and ethical responsibilities.
Katarina Riesner, Linda Hammerich, Denise Jahn, Agnes Ellinghaus, Dietrich Polenz, Lisa Grohmann, Juliane K Unger   +6 more
doaj   +1 more source

The grain refinement potency of bismuth in magnesium [PDF]

, 2016
Copyright © 2016 The Authors. A quantitative model was applied to analyse the grain refinement potency of bismuth in magnesium. The formation of potent Mg-Bi-O intermetallic phases at 0.4wt.% Bi were attributed to a noteworthy reduction in the average ...
Joshi, U, Joshi, Utsavi, Hari Babu, N, Hari Babu, N.   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

From ODP Viewpoint Consistency to Integrated Formal Methods [PDF]

, 2013
Questions asked by research into ODP Viewpoint Consistency led to fundamental questions in refinement and contributed greatly to insights and interest in Integrated Formal Methods; research in those areas is still ongoing, while the answers provided ...
Derrick, John, Boiten, Eerke Albert
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Genetic Conservation and Population Management of Non‐Human Primates: Parentage Determination Using Seven Microsatellite‐Based Multiplexes

Ecology and Evolution
Conservation of non‐human primates receives much attention, with nearly 350 of the more than 520 recorded primate species classified as threatened.
Natasja G. deGroot, Annemiek J. M. deVos‐Rouweler, Corrine M. C. Heijmans, Annet Louwerse, Jorg J. M. Massen, Jan A. M. Langermans, Ronald E. Bontrop, Jesse Bruijnesteijn   +7 more
doaj   +1 more source

Aversion to Desflurane and Isoflurane in Sprague-Dawley Rats (Rattus norvegicus)

Animals, 2020
Carbon dioxide and isoflurane are widely used for killing rats, yet may not truly achieve “euthanasia”, because they elicit aversion. The inhalant anesthetic desflurane is faster acting than isoflurane, representing a potential refinement.
Katrina Frost, Maaria Shah, Vivian S.Y. Leung, Daniel S.J. Pang   +3 more
doaj   +1 more source

Game Refinement Theory and Its Application to Score Limit Games [PDF]

, 2014
This paper presents an application of game refinement theory to score limited sport games badminton and table tennis, in order to observe the effect of recent rule changes on their sophistication.
Hiroyuki Iida, Nossal, Nathan, Nathan Nossal, Iida, Hiroyuki   +3 more
core   +1 more source