Results 71 to 80 of about 553,328 (316)

Structural studies into AM(_2)O(_7) framework materials and parametric Rietveld refinement [PDF]

open access: yes, 2006
This thesis investigates the structural properties of the AM2O7 family of materials, many of which show interesting thermal expansion properties and remarkably complex structures.
Stinton, Graham William
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Ultrafast Interfacial Engineering for Quantifiable Control of Asymmetric Configurations in Nanostructured Janus Membranes

open access: yesAdvanced Science
Janus membranes (JMs) promise advanced liquid separations, but fabrication speed, substrate universality, and precise configurational control remain challenging. Here, we report an ultrafast and universal interfacial engineering strategy to construct JMs
Wenqing Zhang   +7 more
doaj   +1 more source

Tactics of Refinement [PDF]

open access: yesAnais do XIV Simpósio Brasileiro de Engenharia de Software (SBES 2000), 2000
The refinement calculus is a modern technique of formal program development. Its application, however, may lead to long and repetitive developments. In this paper we present a language to write refinement tactics, and present examples of useful tactics.
Marcel Oliveira, Ana Cavalcanti 0001
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Feature Refinement [PDF]

open access: yesFifth IEEE International Conference on Software Engineering and Formal Methods (SEFM 2007), 2007
Development by formal stepwise refinement offers a guarantee that an implementation satisfies a specification. But refinement is frequently defined in such a restrictive way as to disallow some useful development steps. Here we define feature refinement to overcome some limitations of refinement and show its usefulness by applying it to examples taken ...
Steve Reeves, David Streader
openaire   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

tsungtingkuo/refinement v1.0.0

open access: yes, 2018
<p>Learning-Based Concept-Hierarchy Refinement through Exploiting Topology, Content and Social Information</p ...
Tsung-Ting Kuo (8224653)   +3 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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