Results 111 to 120 of about 182,084 (332)

Grover's disease: dermoscopy, reflectance confocal microscopy, and histopathological correlation

Dermatology Practical & Conceptual, 2017
Grover’s disease is a benign condition of unknown origin characterized clinically by an erythematous papulovesicular eruption and histopathologically by intraepidermal clefting and four different patterns of acantholysis: Darier-like, pemphigus-like ...
Francesco Lacarrubba, Simona Boscaglia, Maria Rita Nasca, Rosario Caltabiano, Giuseppe Micali   +4 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Advances in the use of Reflectance Confocal Microscopy in Melanoma

Melanoma Management, 2018
In vivo reflectance confocal microscopy (RCM) is a noninvasive high-resolution skin imaging tool that has become an important adjunct to clinical exam, dermoscopy and histopathology assessment, in the diagnosis and management of melanoma. RCM generates a horizontal view of the skin, whereby cellular and subcellular (e.g., nuclei, melanophages, collagen)
Andréanne Waddell, Phoebe Star, Pascale Guitera   +2 more
openaire   +3 more sources

Anatomical skin segmentation in reflectance confocal microscopy with weak labels

, 2015
Reflectance confocal microscopy (RCM) allows in-vivo microscopic examination of human skin and is emerging as a powerful tool for a wide range of dermatological problems.
Ardigo, Marco, Bradley, Andrew P., Samuel C. Hames, Marco Ardigo, Tarl W. Prow, Soyer, H. Peter, Andrew P. Bradley, Hames, Samuel C., H. Peter Soyer, Prow, Tarl W.   +9 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Reflectance confocal microscopy margin mapping and monitoring of an amelanotic melanoma in situ of the ear

, 2018
In situ amelanotic melanoma represents a diagnostic and therapeutic challenge for clinicians. Poor demarcation of these lesions often results in repeated therapeutic intervention until appropriate clearance has been achieved.
Robinson, Mitchell, McMeniman, Erin, Curchin, Claudia   +2 more
core   +1 more source

Lesions Mimicking Melanoma at Dermoscopy Confirmed Basal Cell Carcinoma: Evaluation with Reflectance Confocal Microscopy [PDF]

, 2018
Background: Atypical basal cell carcinoma (BCC), characterized by equivocal dermoscopic features typical of malignant melanoma (MM), can be difficult to diagnose.
CHESTER, Johanna, NISTICÒ, Steven Paul, MANDEL, Victor Desmond, PELLACANI, Giovanni, DEL DUCA, Ester, GIANNETTI, Luca, STANGANELLI, Ignazio, FARNETANI, Francesca, DI TULLIO, Francesca, NISTICO', Steven Paul, CIARDO, Silvana, PECCERILLO, Francesca, DE CARVALHO, Nathalie, MAZZONI, Laura, KALECI, Shaniko   +14 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

A Compact Laser Imaging System for Concurrent Reflectance Confocal Microscopy and Laser Doppler Flowmetry

IEEE Photonics Journal, 2016
We propose a compact laser feedback interferometry imaging system for concurrent reflectance confocal microscopy and laser Doppler flowmetry. This system acquires both confocal reflectance and Doppler signals in a confocal architecture to image dynamic ...
Alireza Mowla, Thomas Taimre, Yah Leng Lim, Karl Bertling, Stephen J. Wilson, Tarl W. Prow, Aleksandar D. Rakic   +6 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source