Results 31 to 40 of about 7,126 (264)

Analysis of the extension behavior of reflective cracks in asphalt pavements based on dry shrinkage property

open access: yesSN Applied Sciences, 2022
In order to study the extension behavior of dry shrinkage type reflective cracks in asphalt pavements, this paper uses the differential equation theory to derive the calculation formula for the inhomogeneous gradient distribution of dry shrinkage stress ...
Min Min Xiao, Lin Fan
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Continuous monitoring of an intentionally-manufactured crack using an automated welding and in-process inspection system

open access: yesMaterials & Design, 2020
Automated weld deposition coupled with the real-time robotic Non-Destructive Evaluation (NDE) is used in this paper. For performance verification of the in-process inspection system, an intentionally embedded defect, a tungsten rod, is introduced into ...
Yashar Javadi   +8 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Crack Width Analysis of Reinforced Concrete Using FBG Sensor

open access: yesIEEE Photonics Journal, 2019
According to the reflection behavior of the fiber Bragg grating, the monitoring method of reinforced concrete was presented in this paper. A postprocessing method to extract crack openings from a three-dimension finite element computation was proposed ...
Lili Wang   +3 more
doaj   +1 more source

Dynamic crack propagation characteristics of media with bedding under an impact load

open access: yes工程科学学报, 2023
With the gradual development of mines, tunnels, and other underground constructions, theoretical research on the influence of internal defects in rock structure on rock dynamic fracture behavior and related engineering practices are of great importance ...
Yan-bing WANG   +4 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Study on the Effect of Crack Density and Micro-Cracking Block Size of In Situ Softening Semi-Rigid Base

open access: yesBuildings
Reflection cracking in semi-rigid bases is a widespread distress that undermines highway safety. Priority should be given to this issue to ensure the normal performance of large-scale semi-rigid base asphalt pavements that have reached the end of their ...
Liting Yu   +6 more
doaj   +1 more source

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