Results 101 to 110 of about 885,510 (305)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Using meta-reflection to enhance performance [PDF]
, 2009 Much evidence supports the use of reflective practice for personal development, yet it is not commonly used as a learning tool in students. More typically, reflective writing is assessed as a stand-alone piece of work.
Mair, Carolyn
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
REFLECTIVE PRACTICE OF RESEARCH-BASED TEACHING
Babylonia, 2019 In the development project “More languages for all”, teachers of the mother tongue and culture (HSK) in cooperation with teachers of regular classes, try to promote the integration of the first language.
Irène Zingg
doaj
Understanding the experience of experience: a practical model of reflective practice for Coaching [PDF]
International Journal of Evidence Based Coaching and Mentoring, 2004 Coaching is inherently a reflective process. Constructivist theories of learning are well established and greatly inform thinking on coaching. The coaching practitioner literature promotes activities and offers many tools to aid reflection.
Peter Jackson
doaj
When One Dimensional Models Fail: Complexifying Models of Knowledge Construction [PDF]
, 2013 One dimensional models of reflective practice do not incorporate spirituality and social responsibility. Theological reflection, a form of reflective practice, is contextualized by a vision of social responsibility and the use of spirituality.
Gallagher, Suzanne J.
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source