Results 41 to 50 of about 4,161 (177)

Galvanic vestibular stimulation reveals disruption of ipsilesional brainstem pathways in hemiparetic stroke survivors

Experimental Physiology, Volume 111, Issue 7, Page 3381-3397, 1 July 2026.
Abstract The spatiotemporal structure of muscle coordination emerges from the collaboration and competition among cortical, brainstem and spinal pathways onto motor neuron pools, each continuously shaped by task demands, limb position and descending tract integrity.
Angelo Bartsch‐Jiménez, Hesam Azadjou, Francisco J. Valero‐Cuevas   +2 more
wiley   +1 more source

Integration of cortical inputs in the lateral hypothalamus is dominated by the medial prefrontal cortex

The Journal of Physiology, Volume 604, Issue 14, Page 6057-6079, 15 July 2026.
Abstract figure legend The lateral hypothalamus (LH) is a critical controller of innate behaviours such as feeding. It is anatomically connected to specific cortical areas. We mapped these areas using a combination of retrograde tracing and anterograde optogenetic circuit mapping.
Lotte J. A. M. Razenberg, Pieter Nicolaas de Greef, Huibert D. Mansvelder, Mahesh Miikael Karnani   +3 more
wiley   +1 more source

Optimizing assessment of low frequency H-reflex depression in persons with spinal cord injury.

PLoS ONE
Considering the growing interest in clinical applications of neuromodulation, assessing effects of various modulatory approaches is increasingly important. Monosynaptic spinal reflexes undergo depression following repeated activation, offering a means to
Charles J Creech, Jasmine M Hope, Anastasia Zarkou, Edelle C Field-Fote   +3 more
doaj   +1 more source

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

Advanced Science, Volume 13, Issue 34, 19 June 2026.
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang, Jiale Yang, Xi Wu, Jie Li, Fujian Lu, Yiman Li, Xingyu Du, Rong Huang, Jamila Asgar, Jing Wang, Ke Ren, Feipeng Zhu, Changhe Wang, Yehua Gan, Feng Wei, Zhuan Zhou   +15 more
wiley   +1 more source

Generating intrafusal skeletal muscle fibres : Current state of the art and future challenges

Journal of Tissue Engineering, 2020
Intrafusal fibres are a specialised cell population in skeletal muscle, found within the muscle spindle. These fibres have a mechano-sensory capacity, forming part of the monosynaptic stretch-reflex arc, a key component responsible for proprioceptive ...
Philip Barrett, Tom J Quick, Vivek Mudera, Darren J Player   +3 more
doaj   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

Advanced Science, Volume 13, Issue 29, 22 May 2026.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun, Jia‐Jia Wang, Xiang‐Yu Li, Xin‐Yi Lin, Juan Li, Qiu‐Tong Yu, Zi‐Han Wang, Xue‐Ping Gao, Lei Jin, Wei‐Ke Li, Tian‐Lin Cheng, Juan Deng   +11 more
wiley   +1 more source

Organic neuromorphic electronics powering intelligent sensory and edge computing systems

InfoMat, Volume 8, Issue 5, May 2026.
Organic electronic materials are promising candidates for neuromorphic sensing applications, including chemical, physical, visual, and multimodal sensing, owing to their mechanical softness, biocompatibility, and intrinsic ionic–electronic coupling.
Seungjun Woo, Minji Chung, Hyun Woo Song, Seoyoung Kim, Eun Kwang Lee, Joon Hak Oh   +5 more
wiley   +1 more source

A Single Aplysia Neurotrophin Mediates Synaptic Facilitation via Differentially Processed Isoforms

Cell Reports, 2013
Neurotrophins control the development and adult plasticity of the vertebrate nervous system. Failure to identify invertebrate neurotrophin orthologs, however, has precluded studies in invertebrate models, limiting our understanding of fundamental aspects
Stefan R. Kassabov, Yun-Beom Choi, Kevin A. Karl, Harshad D. Vishwasrao, Craig H. Bailey, Eric R. Kandel   +5 more
doaj   +1 more source

Menstrual cycle effects on sex differences in motor control during dynamic balance perturbations

Experimental Physiology, Volume 111, Issue 5, Page 2665-2681, 1 May 2026.
Abstract This study investigated sex differences in neuromuscular responses during dynamic balance perturbations and isometric maximal voluntary contractions (IMVCs) by examining if menstrual cycle (MC) phase and the fluctuations in endogenous hormones influence the observation of sex differences.
Samuli Nevanperä, Ritva S. Mikkonen, Simon Walker, Jarmo M. Piirainen   +3 more
wiley   +1 more source

Reflex inhibition of monosynaptic reflexes by stimulation of type J pulmonary endings [PDF]

The Journal of Physiology, 1970
1. Monosynaptic reflexes, evoked from flexor and extensor hind limb muscle nerves in cats anaesthetized with pentobarbitone sodium, were depressed for several seconds after right intra‐atrial injection of phenyl diguanide. Injection of the drug close to the aortic valves did not produce the same effect on the reflex.
S S, Deshpande, M S, Devanandan
openaire   +2 more sources