Results 51 to 60 of about 4,161 (177)

Respiratory‐Limbic Coupling via a Thalamic Circuit Alleviates Anxiety

Advanced Science, Volume 13, Issue 24, 27 April 2026.
This study delineates a conserved preBötCGlu→PVT→CeA circuit that gates anxiety and respiration. Activation of this circuit is anxiolytic and respiratory‐stabilizing, while its inhibition has the opposite effect. Mechanistically, PVT exerts its anxiolytic action via a disinhibitory microcircuit: its inputs preferentially target CeL GABAergic neurons ...
Shangyu Bi, Xiaoyi Wang, Huichun Luo, Ziteng Yue, Tianjiao Deng, Yuhang Liu, Xinxin Chen, Jianxu Zhao, Luo Shi, Ning Ma, Lingyan Mao, Jing Ding, Jiwen Xu, Ti‐Fei Yuan, Sheng Wang, Fang Yuan   +15 more
wiley   +1 more source

Effect of labyrinth ectomy on the dynamics of extensor and flexor monosynaptic reflex discharges driven by activation of cutaneous and thin muscle afferents in response to intravenous injection of picrotoxin

Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2015
It was found that at intensity of conditioning irritation of 5-15 thresholds of thin muscle nerve flexordigitorumlongusor cutaneous nerve suralisthe dynamics of changing of testing monosynaptic reflex discharges (МSRD) began with their reinforcement by 3-
I. I. Grigorenko, V. N. Gavelya
doaj  

Time Window of Perturbation-Induced Response Triggered by Ankle Motion and Body Sway above the Ankle

Brain Sciences, 2020
We determined the precise time windows of the electromyographic (EMG) response components triggered by ankle motion and by body sway above the ankle. A support surface under the feet of healthy young adult participants in the quiet stance was moved in ...
Koichi Hiraoka, Toru Kuramitsu, Naoki Nii, Miyuki Osumi, Nana Tanaka   +4 more
doaj   +1 more source

The sympathoregulatory region of the mouse rostral brainstem relies on both GABA and glycine to generate inhibitory currents

The Journal of Physiology, Volume 604, Issue 7, Page 2939-2957, 1 April 2026.
Abstract figure legend Our study demonstrates that both GABA and glycine mediate inhibitory postsynaptic currents in the ventrolateral/ventromedial medulla (VLM/VMM) and increasing the activity of inhibitory synapses facilitates glycine release. We found that presympathetic VLM/VMM neurons receive glycinergic inputs, which release both glycine and GABA,
Hong Gao, Lucie D. Desmoulins, Adrien J. R. Molinas, Courtney M. Dugas, Andrea Zsombok, Andrei V. Derbenev   +5 more
wiley   +1 more source

Transcutaneous spinal direct current stimulation increases corticospinal transmission and enhances voluntary motor output in humans

Physiological Reports, 2020
Optimization of motor performance is of importance in daily life, in relation to recovery following injury as well as for elite sports performance.
Tomofumi Yamaguchi, Mikkel M. Beck, Eva R. Therkildsen, Christian Svane, Christian Forman, Jakob Lorentzen, Bernard A. Conway, Jesper Lundbye‐Jensen, Svend S. Geertsen, Jens B. Nielsen   +9 more
doaj   +1 more source

Fatigue‐Induced Neuromuscular Responses Differ Between Endurance‐ and Strength‐Trained Males

European Journal of Sport Science, Volume 26, Issue 3, March 2026.
ABSTRACT This study aimed to investigate the effect of training background on neuromuscular responses to submaximal isometric fatiguing contraction. Eleven strength‐trained (ST) and 11 endurance‐trained (ET) males performed maximal voluntary isometric knee extension contractions (MVIC) and a torque steadiness task at 20% MVIC before and immediately ...
Rui Wu, Madeleine M. Lowery, Giuseppe De Vito, Jiaping Jiang, Che Shao, Wen Luo, Xuanbin Chen, HongWei Hao, Dan Wang   +8 more
wiley   +1 more source

Engaging Gut‐to‐Brain Signalling to Treat Alcohol Use Disorder

Addiction Biology, Volume 31, Issue 3, March 2026.
ABSTRACT According to the 2023 National Survey on Drug Use and Health (NSDUH), 28.9 million people ages 12 and older in the United States had alcohol use disorder (AUD) in the past year. Although chronic alcohol use contributes to numerous health disorders as well as being an economic burden, there are few medications approved for treatment of AUD, and
Paula L. Hoffman, Giordano de Guglielmo, Valentina Vengeliene, Wolfgang Kunze, Christina L. Lebonville, Jerome D. Swinny, Amanda J. Roberts, Olivier George, Karen‐Anne McVey Neufeld, Alexandra Dunbar, Laura M. Saba, Ruolin Ma, Leandro F. Vendruscolo, Howard C. Becker, Rainer Spanagel, Boris Tabakoff   +15 more
wiley   +1 more source

Extrasynaptic α6 subunit-containing GABAA receptors modulate excitability in turtle spinal motoneurons.

PLoS ONE, 2014
Motoneurons are furnished with a vast repertoire of ionotropic and metabotropic receptors as well as ion channels responsible for maintaining the resting membrane potential and involved in the regulation of the mechanisms underlying its membrane ...
Carmen Andres, Justo Aguilar, Ricardo González-Ramírez, David Elias-Viñas, Ricardo Felix, Rodolfo Delgado-Lezama   +5 more
doaj   +1 more source

A High‐Resolution Transcriptomic Atlas of Cell Types in the Ventral Visual Thalamus

Journal of Neurochemistry, Volume 170, Issue 3, March 2026.
Visual information from the eyes travels from retinal ganglion cells (RGCs) to reach the brain through several relay centers. One of these centers, the ventral lateral geniculate nucleus (vLGN), is much less understood than others. In this study, we created the first detailed map of the different cell types found in the mouse vLGN.
Katelyn Stebbins, Maira Jalil, Parsa Khaksar, Addison N. Webster, John Campbell, Michael A. Fox   +5 more
wiley   +1 more source

Sensory gating of an embryonic zebrafish interneuron during spontaneous motor behaviors

Frontiers in Neural Circuits, 2014
In all but the simplest monosynaptic reflex arcs, sensory stimuli are encoded by sensory neurons that transmit a signal via sensory interneurons to downstream partners in order to elicit a response.
Laura Danielle Knogler, Pierre eDrapeau
doaj   +1 more source