Results 101 to 110 of about 152,149 (307)

The carotid body as a therapeutic target for the treatment of sympathetically mediated diseases [PDF]

, 2013
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Abdala, Ana P, Burchell, Amy, Engleman, Zoar J, Fudim, Marat, Gourine, Alexander V, Hart, Emma C J, Lobo, Mel, Marina, Nepthali, McBryde, Fiona D, Nightingale, Angus, Patel, Nik, Paton, Julian F R, Ratcliffe, Laura E K, Sobotka, Paul A   +13 more
core   +2 more sources

Rational Design of Printable Carbon Nanotube Transparent Conductive Films via Data‐Driven and Mechanistic Insights

Advanced Functional Materials, EarlyView.
A machine learning and simulation‐guided strategy is demonstrated for gentle, non‐sonication dispersion of carbon nanotubes, preserving structural integrity and performance. This approach enables transparent conductive films with low sheet resistance, high transmittance, and sub‐20 µm printability.
Ying Zhou, Ken‐ichi Nomura, Shun Muroga, Makoto Yoneya, Don N. Futaba, Takeo Yamada, Reiko Azumi, Kenji Hata   +7 more
wiley   +1 more source

Sensitized vasoactive C-nociceptors: key fibers in peripheral neuropathic pain

PAIN Reports, 2019
. Introduction:. Multiple mechanisms are involved in the development and persistence of neuropathic pain. Some patients with nerve damage will remain painless and develop a “loss of function” phenotype, whereas others develop painful neuropathies ...
Julia Forstenpointner, Dennis Naleschinski, Gunnar Wasner, Philipp Hüllemann, Andreas Binder, Ralf Baron   +5 more
doaj   +1 more source

Influence of muscle preactivation of the lower limb on impact dynamics in case of frontal collision

, 2005
Accidentology or shock biomechanics are research domains mainly devoted to the development of safety conditions for the users of various transport modes in case of an accident. The objective of this study was to improve the knowledge of the biomechanical
Chavet, Pascale, Nicol, Caroline, Pithioux, Martine, St-Onge, Nancy   +3 more
core   +4 more sources

Doxorubicin‐Loaded Metal–Organic Framework for Ferroptosis‐Enhanced Chemotherapy Through Sustained Zn Release and Glutathione Peroxidase Downregulation

Advanced Healthcare Materials, EarlyView.
A robust zinc‐based metal–organic framework (ZnMOF) enables dual functions of doxorubicin delivery and sustained Zn2+ release to trigger ferroptosis‐enhnaced chemotherapy. DOX@ZnMOF effectively depletes intracellular glutathione, suppresses GPX4, and elevates reactive oxygen species, leading to efficient oxidative DNA damage and apoptosis.
Xin Ma, Chenghua Deng, Chaoyu Wang, Langston Tilman, Jinhong Li, Wenbin Lin   +5 more
wiley   +1 more source

Cooperative Oxygen Sensing by the Kidney and Carotid Body in Blood Pressure Control

Frontiers in Physiology, 2017
Oxygen sensing mechanisms are vital for homeostasis and survival. When oxygen levels are too low (hypoxia), blood flow has to be increased, metabolism reduced, or a combination of both, to counteract tissue damage.
Daniela Patinha, Daniela Patinha, Wioletta Pijacka, Julian F. R. Paton, Maarten P. Koeners, Maarten P. Koeners   +5 more
doaj   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Effectiveness of reflex integration approach and play therapy on functionality in patients with spastic cerebral palsy: a comparative study

Bulletin of Faculty of Physical Therapy
Background Cerebral palsy (CP) is a group of permanent disorders affecting movement and posture due to non-progressive damage to the developing brain.
Nidhi V. Patel, Anjan Rajeshkumar Desai
doaj   +1 more source

Mesenteric Vascular Dysregulation and Intestinal Inflammation Accompanies Experimental Spinal Cord Injury

, 2016
Cervical and high thoracic spinal cord injury (SCI) drastically impairs autonomic nervous system function. Individuals with SCI at thoracic spinal-level 5 (T5) or higher often present cardiovascular disorders that include resting systemic arterial ...
Besecker, Emily Swartz, Cooper, Timothy K., Deiter, Gina M., Holmes, Gregory Michael, Pironi, Nicole   +4 more
core   +1 more source

Operant conditioning of spinal reflexes to improve function recovery after CNS damage

The FASEB Journal, 2013
The elicitation of spinal reflexes, which has traditionally been used to monitor basic motor and sensory functions, is now finding uses for modifying CNS pathways and thereby restoring more effective function after spinal cord injuries and in other disorders.
openaire   +1 more source