Results 81 to 90 of about 191,226 (280)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
In this article the professional competence of modern educators is considered, which presupposes the possession of an information culture due to the increased requirements imposed by the modernization of the educational system.
Marta I. Diri
doaj
Intentional Cognitive Models with Volition
Man’s intellectual capacity remains an enigma, as it is both the subject and the means of analysis. If one is to assume quantum-wave dualism in physics then the state of the world depends on the instruments we use for observation.
Howard, Newton, Qusaibaty, Ammar
core
Intersecting brane world models from D8-branes on (T^2 x T^4/Z_3)/Omega R_1 type IIA orientifolds
We present orientifold models of type IIA string theory with D8-branes compactified on a two torus times a four dimensional orbifold. The orientifold group is chosen such that one coordinate of the two torus is reversed when applying worldsheet parity ...
A. Sagnotti +28 more
core +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Auto-Audit of Digital Earth and Beyond
The question is posed: "If we use the Digital Earth to verify the results of an audit (e.g. land cadastre) conducted in a traditional format, who can verify the Digital Earth itself?" The answer is, "The Digital Earth can audit itself.
Yuri Baturin, Prof.
doaj

