Results 41 to 50 of about 1,973,166 (180)

Heterogeneity of cough hypersensitivity mediated by TRPV1 and TRPA1 in patients with chronic refractory cough

Respiratory Research, 2019
Background The differential sensitivity of cough to antitussive therapies implies the existence of heterogeneity in cough hypersensitivity, but how such heterogeneity is expressed across individual patients is poorly understood.
Li Long, Hongmei Yao, Jing Tian, Wei Luo, Xinxin Yu, Fang Yi, Qiaoli Chen, Jiaxing Xie, Nanshan Zhong, Kian Fan Chung, Kefang Lai   +10 more
doaj   +1 more source

The Severity of Chronic Cough Diary (SCCD): development and content validation of a novel patient-reported outcome instrument for evaluating the symptom experience of chronic cough

Journal of Patient-Reported Outcomes, 2023
Background Refractory chronic cough (RCC), a cough lasting longer than 8 weeks with an unexplained underlying etiology and unresponsive to conventional treatment, can have substantial effects on patients’ quality of life.
Margarita de la Orden Abad, Claudia Haberland, Hayley Karn, Anne Skalicky, Asha Hareendran   +4 more
doaj   +1 more source

Effectiveness of virtual, group cough modulation therapy for chronic refractory cough

ERJ Open Research
Chronic refractory cough is common. A virtual, group-based approach that delivers cough suppression therapy was associated with improvements in cough severity visual analogue scale and Leicester cough questionnaire scores. https://bit.ly/4ltwNul.
Emily C. Kear, Zander J. Williams, Julia Selby, Chang Lu, Caroline J. Jolley, Peter S.P. Cho, Barnaby Hirons, Surinder S. Birring, James H. Hull   +8 more
doaj   +3 more sources

Treatment of recalcitrant cough with baclofen

Italian Journal of Medicine, 2013
Background: Chronic dry cough is a debilitating symptom often refractory to standard antitussive therapy. It may result from increased sensitivity of the cough reflex. Baclofen, an agonist of gamma-aminobutyric acid (GABA), has been shown, in animals, to
Paolo Agostinis, Paola Bardus, Vito Di Piazza, Ferdinando Dassi, Nadia Durigon, Alfio Englaro, Patrizia Grillo, Euro Marchetti, Tiziano Petris, Enzo Sabatini   +9 more
doaj   +1 more source

What is Chronic Cough? Terminology [PDF]

, 2019
Terminology used to define clinical cough is based on features such as duration, underlying causes and associated characteristics such as whether the cough is 'dry' or 'productive'.
McGarvey, Lorcan, Gibson, Peter G
core   +1 more source

A register-based study: cough - a frequent phenomenon in the adult population

BMC Pulmonary Medicine, 2022
Background Chronic cough, more than 8 weeks, can either be without co-morbidity called unexplained chronic cough (UCC) or with co-morbidity called refractory chronic cough (RCC). Using datasets from the Danish National Prescription Registry (Prescription
Vibeke Backer, Andreas Porsborg, Victor Hansen, Tina Skjold, Johannes Martin Schmid, Mette Kehlet, Christian Torp-Pedersen, Kristian Aasbjerg   +7 more
doaj   +1 more source

Cough symptom severity in patients with refractory or unexplained chronic cough: a systematic survey and conceptual framework

European Respiratory Review, 2021
Background Cough severity represents an important subjective endpoint in assessing the effectiveness of therapies for patients with chronic cough. Although cough-specific quality of life questionnaires exist, a widely available cough severity instrument ...
Elena Kum, Gordon H. Guyatt, Tahira Devji, Yuting Wang, Layla Bakaa, Lucy Lan, Eva Liu, Alexander Mastrolonardo, Rachel Couban, Paul M. O'Byrne, Imran Satia   +10 more
doaj   +1 more source

The Past, Present, and Future Care for Refractory Chronic Cough in Children and Adults. [PDF]

J Clin Med
Chronic cough without explanation or diagnosis has been described in medical books for over 300 years. Since 1977, some comorbidities, such as gastroesophageal reflux and post-nasal drip, have been attributed to be causes of otherwise unexplained chronic
Weinberger M, Anbar RD, Buettner D.
europepmc   +2 more sources

The Benefit of Supplemental Cough Suppression Therapy for Chronic Refractory Cough

Journal of The Korean Society of Laryngology, Phoniatrics and Logopedics, 2022
Background and Objectives Cough suppression therapy (CST) is a physiotherapy that can be used for patients with chronic refractory cough (CRC). We aimed to investigate the efficacy of CST for CRC.Materials and Method A prospective randomized controlled trial was conducted in 27 patients with CRC.
Yong Jun Yoo, Hye Jin Park, Myung Woul Han, Ji Won Kim   +3 more
openaire   +1 more source

Prevalence and risk factors for refractory and untreated chronic cough in the Canadian Longitudinal Study of Aging

ERJ Open Research
Background Chronic cough, defined as a persistent cough lasting >8 weeks, affects 16% of Canadian adults in the community. Chronic cough can be classified as refractory chronic cough when cough persists despite treatment of any identifiable underlying ...
Wafa Hassan, Alexandra J. Mayhew, Nazmul Sohel, Kieran J. Killian, Paul M. O'Byrne, Parminder Raina, Imran Satia   +6 more
doaj   +1 more source