Results 41 to 50 of about 1,855,208 (237)

Adjunctive treatment with oral AKL1, a botanical nutraceutical, in chronic obstructive pulmonary disease [PDF]

, 2014
Claire Brockwell,1 Sundari Ampikaipakan,1,2 Darren W Sexton,1 David Price,3,4 Daryl Freeman,5 Mike Thomas,6 Muzammil Ali,4 Andrew M Wilson1,21Norwich Medical School, University of East Anglia, Norwich, UK; 2Norfolk and Norwich University Hospital ...
Freeman, D, Wilson, AM, Thomas, Mike, Brockwell, Claire, Ampikaipakan, Sundari, Thomas M, Ampikaipakan, S, Ali, M, Sexton, Darren W., Freeman, Daryl, Brockwell C, Ampikaipakan S, Thomas, M., Wilson, Andrew M., Brockwell, C, Freeman D, Ali M, Sexton, DW, Sexton DW, Price, D, Price, David, Ali, Muzammil, Thomas, M, Price D, Wilson AM   +24 more
core   +1 more source

Heterogeneity of cough hypersensitivity mediated by TRPV1 and TRPA1 in patients with chronic refractory cough

Respiratory Research, 2019
Background The differential sensitivity of cough to antitussive therapies implies the existence of heterogeneity in cough hypersensitivity, but how such heterogeneity is expressed across individual patients is poorly understood.
Li Long, Hongmei Yao, Jing Tian, Wei Luo, Xinxin Yu, Fang Yi, Qiaoli Chen, Jiaxing Xie, Nanshan Zhong, Kian Fan Chung, Kefang Lai   +10 more
doaj   +1 more source

The Severity of Chronic Cough Diary (SCCD): development and content validation of a novel patient-reported outcome instrument for evaluating the symptom experience of chronic cough

Journal of Patient-Reported Outcomes, 2023
Background Refractory chronic cough (RCC), a cough lasting longer than 8 weeks with an unexplained underlying etiology and unresponsive to conventional treatment, can have substantial effects on patients’ quality of life.
Margarita de la Orden Abad, Claudia Haberland, Hayley Karn, Anne Skalicky, Asha Hareendran   +4 more
doaj   +1 more source

Influence of lung function on course of disease and response to antibiotic therapy in adult primary care patients with acute cough: a post hoc analysis of patients enrolled in a prospective multicentre study [PDF]

, 2014
BACKGROUND: In acute cough patients, impaired lung function as present in chronic lung conditions like asthma and chronic obstructive pulmonary disease (COPD) are often thought to negatively influence course of disease, but clear evidence is lacking.AIMS:
Verheij, Theo J M, Leven, Margareta, Moore, Michael, Verheij, TJ, Thomas, Mike, Verheij, Theo J.M., Stuart, B, Hood, K, Coenen, Samuel, Stuart, Beth, Goossens, Herman, Goossens, H, Little, Paul, Moore, M, Coenen, S, Little, P, van Erp, Nicole, Thomas, M, Hood, Kerenza, van Erp, N, Butler, Chris C., Butler, CC, Leven, M   +22 more
core   +1 more source

Treatment of recalcitrant cough with baclofen

Italian Journal of Medicine, 2013
Background: Chronic dry cough is a debilitating symptom often refractory to standard antitussive therapy. It may result from increased sensitivity of the cough reflex. Baclofen, an agonist of gamma-aminobutyric acid (GABA), has been shown, in animals, to
Paolo Agostinis, Paola Bardus, Vito Di Piazza, Ferdinando Dassi, Nadia Durigon, Alfio Englaro, Patrizia Grillo, Euro Marchetti, Tiziano Petris, Enzo Sabatini   +9 more
doaj   +1 more source

A register-based study: cough - a frequent phenomenon in the adult population

BMC Pulmonary Medicine, 2022
Background Chronic cough, more than 8 weeks, can either be without co-morbidity called unexplained chronic cough (UCC) or with co-morbidity called refractory chronic cough (RCC). Using datasets from the Danish National Prescription Registry (Prescription
Vibeke Backer, Andreas Porsborg, Victor Hansen, Tina Skjold, Johannes Martin Schmid, Mette Kehlet, Christian Torp-Pedersen, Kristian Aasbjerg   +7 more
doaj   +1 more source

Non-pharmacological interventions for chronic cough: the past, present and future [PDF]

, 2019
Non-pharmacological interventions have been explored in people with refractory chronic cough. Normally delivered by Physiotherapists and or Speech and Language Therapists, these interventions aim to educate patients about their cough, provide them with ...

core   +1 more source

Cough symptom severity in patients with refractory or unexplained chronic cough: a systematic survey and conceptual framework

European Respiratory Review, 2021
Background Cough severity represents an important subjective endpoint in assessing the effectiveness of therapies for patients with chronic cough. Although cough-specific quality of life questionnaires exist, a widely available cough severity instrument ...
Elena Kum, Gordon H. Guyatt, Tahira Devji, Yuting Wang, Layla Bakaa, Lucy Lan, Eva Liu, Alexander Mastrolonardo, Rachel Couban, Paul M. O'Byrne, Imran Satia   +10 more
doaj   +1 more source

The Benefit of Supplemental Cough Suppression Therapy for Chronic Refractory Cough

Journal of The Korean Society of Laryngology, Phoniatrics and Logopedics, 2022
Background and Objectives Cough suppression therapy (CST) is a physiotherapy that can be used for patients with chronic refractory cough (CRC). We aimed to investigate the efficacy of CST for CRC.Materials and Method A prospective randomized controlled trial was conducted in 27 patients with CRC.
Yong Jun Yoo, Hye Jin Park, Myung Woul Han, Ji Won Kim   +3 more
openaire   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source