Management of Non-Pharmacologic Therapy for Chronic Refractory Cough: Mechanism, Composition, Applicable Population, and Assessment [PDF]
Heliyon, 2023 Chronic cough is common in the clinic and can seriously affect the quality of life of patients. Following the existing guidelines for treatment, refractory chronic cough is defined as a clinical condition in which the cause of the cough remains unclear ...
Xianghuai Xu, Yanzi Peng, Lingdan Yuan
exaly +4 more sources
State of the Art for Refractory Cough: Multidisciplinary Approach [PDF]
Tuberculosis and Respiratory Diseases, 2023 Chronic cough is a common problem that can be refractory to medical treatment. Nonpharmaceutical management of chronic cough has an important role in well selected patients.
Anne E. Vertigan
doaj +4 more sources
Gabapentin for Chronic Refractory Cough: A System Review and Meta-Analysis [PDF]
Heliyon, 2023 Objective: To evaluate the efficacy and safety of gabapentin in the treatment of chronic refractory cough by Meta-Analysis. Methods: Literatures were retrieved from PubMed, Embase (OvidIP), Cochrane Library, CNKI, VIP, Wanfang Database and China ...
Deyun Cheng, Yongchun Shen
exaly +4 more sources
Heterogeneity of cough hypersensitivity mediated by TRPV1 and TRPA1 in patients with chronic refractory cough [PDF]
Respiratory Research, 2019 Background The differential sensitivity of cough to antitussive therapies implies the existence of heterogeneity in cough hypersensitivity, but how such heterogeneity is expressed across individual patients is poorly understood.
Li Long +10 more
doaj +4 more sources
Efficacy and tolerability of zinc acetate for treatment of chronic refractory cough: pilot randomised futility trial [PDF]
ERJ Open Research, 2023 Background: Cough is the most reported symptom in the United States, with chronic refractory cough representing significant morbidity to patients. Zinc acetate may have beneficial effects in the cough reflex pathway.
Aparna Balasubramanian +12 more
doaj +2 more sources
The efficacy of gabapentin for the treatment of refractory cough associated with interstitial lung disease: study protocol for a randomized, double-blind and placebo-controlled clinical trial [PDF]
Trials, 2022 Introduction Gabapentin, a neurotransmitter modulator, is thought to treat refractory cough associated with interstitial lung disease by improving cough hypersensitivity.
Ronglin Gao +9 more
doaj +2 more sources
Frequent Sips of the Water for the Management of Gastroesophageal Reflux Induced Refractory Cough: A Case Report and Review of the Literature [PDF]
Case Reports in Gastrointestinal Medicine, 2019 Background. Chronic cough is often associated with gastroesophageal reflux disease (GERD). The role of gastroenterologist in the management of the chronic cough is to identify and manage GERD. Ineffective esophageal motility is often associated with GERD
Hassan Tariq +4 more
doaj +2 more sources
Prevalence and risk factors for refractory and untreated chronic cough in the Canadian Longitudinal Study of Aging [PDF]
ERJ Open ResearchBackground Chronic cough, defined as a persistent cough lasting >8 weeks, affects 16% of Canadian adults in the community. Chronic cough can be classified as refractory chronic cough when cough persists despite treatment of any identifiable underlying ...
Wafa Hassan +6 more
doaj +2 more sources
Abnormal breathing pattern features in chronic refractory cough [PDF]
ERJ Open ResearchBackground Chronic refractory cough (CRC) is a challenging condition that responds to speech pathology intervention. Clinical observation suggests abnormal breathing patterns occur in CRC and may be indirectly addressed as part of behavioural treatment ...
Jordan Jeffery +3 more
doaj +2 more sources
Unraveling the neuro-immune axis in cough hypersensitivity: from pathogenesis to synergistic management [PDF]
Frontiers in MedicineCough Hypersensitivity Syndrome (CHS) stands as the definitive pathological phenotype of refractory chronic cough, characterized by a sensory nervous system that over-reacts to even trivial, low-threshold stimuli.
Dingyi Shi +12 more
doaj +2 more sources