Results 41 to 50 of about 26,442 (182)

New insights in the diagnosis of chronic refractory cough [PDF]

Respiratory Medicine, 2018
Chronic Refractory Cough (CRC) is a common condition that significantly impairs patients' quality of life. Unfortunately, in many situations patients continue to experience CRC in spite of following published guidelines for diagnosis and treatment.99 patients were referred to National Jewish Health (NJH), a specialty respiratory center for evaluation ...
James T, Good, Donald R, Rollins, Christena A, Kolakowski, Allen D, Stevens, Joshua L, Denson, Richard J, Martin   +5 more
openaire   +2 more sources

The Benefit of Supplemental Cough Suppression Therapy for Chronic Refractory Cough

Journal of The Korean Society of Laryngology, Phoniatrics and Logopedics, 2022
Background and Objectives Cough suppression therapy (CST) is a physiotherapy that can be used for patients with chronic refractory cough (CRC). We aimed to investigate the efficacy of CST for CRC.Materials and Method A prospective randomized controlled trial was conducted in 27 patients with CRC.
Yong Jun Yoo, Hye Jin Park, Myung Woul Han, Ji Won Kim   +3 more
openaire   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source

System‐Local Axes and Metabolic Reprogramming From Health to Response in House Dust Mite‐Specific Subcutaneous Immunotherapy for Allergic Rhinitis

iMetaMed, EarlyView.
This study delineated nasal‐plasma metabolic reprogramming in house dust mite‐allergic rhinitis (HDM‐AR) and subcutaneous immunotherapy (SCIT) response, showing compartment‐specific signatures dominated by nasal lipid‐redox and plasma nucleotide‐NAD+ axes and across the HC–HDM‐AR–SCIT response continuum, dual‑compartment metabolites exhibited ...
Bixing Fang, Fei Pan, Yachun Li, Yimeng Wang, Ze Wang, Zhiheng Huang, Ming Chen, Yun Li, Mengli Huang, Cheng Guo, Chubo Xie, Lina Dong, Yadong Gao, Zhuohang Yu   +13 more
wiley   +1 more source

Therapeutic‐dose verapamil‐induced cardiogenic shock in an older patient: a case report

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background Calcium channel blocker (CCB) toxicity most commonly follows deliberate overdose. However, severe toxicity at therapeutic doses may occur in susceptible individuals. Severe CCB toxicity often presents with clinical features of bradycardia, hypotension, hyperglycaemia, and lactic acidosis.
Christopher Thuring, Maria Carey, Timothy Webber, Biswadev Mitra   +3 more
wiley   +1 more source

Laryngeal Cryotherapy for Neurogenic Cough: Safety, Feasibility, and Prospective Outcomes

The Laryngoscope, EarlyView.
A prospective clinical trial investigated the safety and clinical outcomes of office‐based selective laryngeal cryotherapy for patients with refractory chronic cough. Patient were followed for 6 months posttreatment and had durable improvement in cough severity index and urge‐to‐cough scores and no serious long term adverse effects.
Shumon I. Dhar, Eric Allen, Yun‐Lun Liu, Alexandra D. D'Oto, Rishi Suresh, Adrianna Shembel, Ted Mau   +6 more
wiley   +1 more source

The Severity of Chronic Cough Diary (SCCD): development and content validation of a novel patient-reported outcome instrument for evaluating the symptom experience of chronic cough

Journal of Patient-Reported Outcomes, 2023
Background Refractory chronic cough (RCC), a cough lasting longer than 8 weeks with an unexplained underlying etiology and unresponsive to conventional treatment, can have substantial effects on patients’ quality of life.
Margarita de la Orden Abad, Claudia Haberland, Hayley Karn, Anne Skalicky, Asha Hareendran   +4 more
doaj   +1 more source

Radiofrequency Neurolysis of the Posterior Nasal Nerve: A Systematic Review and Meta‐Analysis

The Laryngoscope, EarlyView.
Radiofrequency neurolysis of the posterior nasal nerve significantly improves symptoms of chronic rhinitis, including nasal obstruction and rhinorrhea, while demonstrating a favorable safety profile. This systematic review and meta‐analysis supports the procedure as an effective minimally invasive treatment, although additional high‐quality randomized ...
Eyad Jamileh, Fahad Muhammad, Mohamed Xamza, Khadijah Ahmed, Abdullah Ahmed, Munir Ahmed   +5 more
wiley   +1 more source

Association of Glucagon‐Like Peptide—1 Receptor Analogues and Laryngeal Symptoms in Obese Adults

The Laryngoscope, EarlyView.
Table 1 succinctly quantifies the time‑dependent association between GLP‑1RA/GIP therapy and laryngeal symptoms, demonstrating modest but statistically robust increases in outcomes such as cough and voice/resonance disorders by 6 months. It provides clinically actionable absolute risks, odds ratios, and hazard ratios that can directly inform counseling,
Priyanka Shah, David Kayekjian, Shaun A. Nguyen, Kirsten Meenan, Ashli K. O’Rourke   +4 more
wiley   +1 more source

Real-world usage and response to gefapixant in refractory chronic cough

ERJ Open Research
Background The real-world efficacy of the P2X3 antagonist gefapixant, a new class of antitussive for refractory chronic cough, is not yet fully understood.
Hisako Matsumoto, Yoshihiro Kanemitsu, Motoki Ohe, Hiroshi Tanaka, Kunihiko Terada, Koichi Nishi, Ryo Atsuta, Johsuke Hara, Junpei Saito, Mitsuhide Ohmichi, Tamotsu Ishizuka, Teruaki Nishiuma, Hideki Inoue, Naoto Watanabe, Tatsuya Nagano, Tetsuya Ueda, Haruhiko Ogawa, Shigeru Endo, Takeshi Suzuki, Toshiyuki Kita, Katsuya Fujimori, Yoshihisa Ishiura, Masaki Fujimura, Akio Niimi   +23 more
doaj   +1 more source