Results 71 to 80 of about 988,764 (283)

Donanemab-associated clinical improvement in Alzheimer's disease presenting predominantly with neuropsychiatric symptoms: A case report

Journal of Alzheimer's Disease Reports
Late-life depression may mask Alzheimer's disease (AD). We report a 78-year-old man with treatment-refractory depressive and anxiety symptoms accompanied by paroxysmal somatic attacks, unresponsive to psychotropic treatment and modified electroconvulsive
Yehao Jiang, Huamei Lin, Bo Hong, Ling Yue   +3 more
doaj   +1 more source

The Role of Glutamatergic and Dopaminergic Genes in Resistant Schizophrenia: A Systematic Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Psychosis is a heterogeneous disorder, with approximately one‐third of patients experiencing treatment resistance, predominantly among individuals diagnosed with Schizophrenia. Treatment‐resistant schizophrenia (TRS) may stem from a distinct biological signature, involving abnormalities in the dopaminergic and glutamatergic systems.
Maria Teresa Moreno‐Calle, Silvia Iñiguez‐Barrio, Maria Aurora Arrue, Leire Erkoreka   +3 more
wiley   +1 more source

Efficacy and safety of ketamine for unipolar refractory depression: an overview of systematic reviews

Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde
Purpose: To analyze the evidence of efficacy and safety of the use of intravenous ketamine for adults with refractory unipolar major depression. Methods: This is an overview of systematic reviews performed according to the PRISMA (Preferred Reporting ...
Gabriela Ribeiro PENA, Fernando Henrique ZONZINI, Aline F. BONETTI   +2 more
doaj   +1 more source

Influence of Molecular Genetic Classes on Behavior in Prader‐Willi Syndrome

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT A wide range of behavioral phenotypes has been described in PWS patients including autism spectrum disorder (ASD). The prevalence of behavioral disorders was studied in 292 participants over 3 years with genetically confirmed PWS (N = 164 females and N = 128 males) with deletion (N = 182) and mUPD (maternal uniparental disomy) (N = 99).
Ranim Mahmoud, Merlin G. Butler, Wai Park, Jennifer L. Miller, Daniel J. Driscoll, June‐Anne Gold, Virginia Kimonis   +6 more
wiley   +1 more source

Genetic Variants of Na+,K+‐ATPase Associated With Neurological Disorders: A Systematic Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Neurological disorders encompass a wide range of severe symptoms and manifestations, many of which are associated with genetic variants that affect ionic homeostasis. Na+,K+‐ATPase, a transmembrane enzyme responsible for maintaining electrochemical gradients in cells, plays a crucial role in neuronal excitability and brain function.
Giovana Kummer da Rosa, Leandro Rodrigo Ribeiro, Jéssica Lorena Bariviera, Mauro Schneider Oliveira   +3 more
wiley   +1 more source

Determinants of Difficult‐to‐Manage and Treatment‐Refractory Axial Spondyloarthritis: A Cross‐Sectional Analysis Within a Longitudinal Cohort

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to estimate the prevalence of difficult‐to‐manage (D2M) and treatment‐refractory (TR) axial spondyloarthritis (axSpA) and to identify factors associated with D2M and TR disease in a longitudinal cohort. Methods We performed a cross‐sectional analysis on data from the Schroeder Arthritis Institute Spondylitis ...
Patricia Remalante‐Rayco, Laura Passalent, Tina Chim, Hannah Vijayan, Manal Alnasser, Zeynep Baskurt, Robert D. Inman, Nigil Haroon, Denis Poddubnyy   +8 more
wiley   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source

Refractory concrete.

, 1978
Symposium held Mar. 17, 1977, sponsored by ACI Committee 547, Refractory Concrete.Includes bibliographical references and ...
Symposium on Refractory ConcreteMarch 17, 1977San Diego, California, ACI Committee 547, Refractory Concrete.   +1 more
core  

Offspring of parents with recurrent depression: which features of parent depression index risk for offspring psychopathology? [PDF]

, 2012
Background: Parental depression is associated with an increased risk of psychiatric disorder in offspring, although outcomes vary. At present relatively little is known about how differences in episode timing, severity, and course of recurrentdepression ...
Sellers, R., Frances Rice (11378531), Sellers, Ruth, Harold, G.T., Potter, Robert, Stephan Collishaw, Nicholas Craddock (613070), Anita Thapar (766569), Robert Potter (3455717), Daniel Smith (6120), Daniel Smith, Anita Thapar, Gordon T. Harold, Craddock, Nicholas John, Stephan Collishaw (766570), Becky Mars, Smith, Daniel, Thapar, Anita, Ruth Sellers (4465924), Ruth Sellers, Harold, Gordon Thomas, Rice, Frances, Thapar, A., Collishaw, S., Thapar, Ajay Kumar, Thapar, Ajay, Robert Potter, Craddock, N., Ajay Thapar, Ajay Thapar (16221035), Collishaw, Stephan, Becky Mars (766567), Gordon Harold (4464610), Potter, R., Craddock, Nicholas, Frances Rice, Rice, F., Harold, Gordon T, Mars, Becky, Nicholas Craddock, Mars, B., Smith, Daniel J., Smith, D.   +42 more
core   +1 more source