Results 91 to 100 of about 1,340,212 (344)

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Wildfires and climate change push low-elevation forests across a critical climate threshold for tree regeneration

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Changes in climate and disturbance regimes may cause abrupt shifts in vegetation communities. Identifying climatic conditions that can limit tree regeneration is important for understanding when and where wildfires may catalyze such changes.
K. Davis   +8 more
semanticscholar   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

open access: yesFEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji   +3 more
wiley   +1 more source

A retinoraphe projection regulates serotonergic activity and looming-evoked defensive behaviour

open access: yesNature Communications, 2017
Neural circuits underlying innate fear are only partially understood. Huanget al. identify a subset of retinal ganglion cells that project to both the dorsal raphe nucleus and the superior colliculus, and show that these RGCs mediate looming-evoked ...
Lu Huang   +15 more
doaj   +1 more source

Tendon vasculature in health and disease.

open access: yesFrontiers in Physiology, 2015
Tendons represent a bradytrophic tissue which is poorly vascularized and, compared to bone or skin, heal poorly. Usually, a vascularized connective scar tissue with inferior functional properties forms at the injury site.
Herbert eTempfer   +3 more
doaj   +1 more source

Microglia dynamics in retinitis pigmentosa model: formation of fundus whitening and autofluorescence as an indicator of activity of retinal degeneration

open access: yesScientific Reports, 2020
In patients with retinitis pigmentosa (RP), color fundus photography and fundus autofluorescence (FAF) have been used to estimate the disease progression.
Kenichi Makabe   +4 more
doaj   +1 more source

REGENERATION OF BONE [PDF]

open access: yesThe American Journal of the Medical Sciences, 1916
n ...
openaire   +3 more sources

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

INTER-ACT: prevention of pregnancy complications through an e-health driven interpregnancy lifestyle intervention – study protocol of a multicentre randomised controlled trial

open access: yesBMC Pregnancy and Childbirth, 2017
Background Excessive maternal pre-pregnancy and gestational weight gain are related to pregnancy- and birth outcomes. The interpregnancy time window offers a unique opportunity to intervene in order to acquire a healthy lifestyle before the start of a ...
Annick Bogaerts   +5 more
doaj   +1 more source

REGENERATION OF THE CORNEA [PDF]

open access: yesJournal of the American Medical Association, 1909
It has long been known that the epithelium of the cornea would regenerate itself after being destroyed intentionally or by accident. Haller 1 as early as 1763, in his "Elementary Physiology of the Human Body," asserts that regeneration of the cornea takes place, and even the oldest ophthalmologists 2 assume that regeneration of corneal tissue occurs ...
openaire   +3 more sources

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