Results 111 to 120 of about 2,200,062 (357)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Intimacy

Regeneration
A multimodal collaboration between artists, writers, and scholars. This piece emerged from an expedition to the Arctic archipelago as part of the Arctic Circle Residency in Autumn 2022.
Alexandra Lockhart, Dianne Chisholm, Hannah Larrabee, Jia-Jen Lin, Sarah Gerats, Zoriça Kelly Markovich   +5 more
doaj   +2 more sources

Shoot and plantlet regeneration from meristems of Dioscorea rotundata Poir and Dioscorea alata L. [PDF]

, 2008
In vitro culture media capable of regenerating moderate to high shoots and/or plantlets from meristems of two yam species - Dioscorea rotundata and Dioscorea alata within comparable duration of 10 weeks as commonly obtained in other monocots and root and
Adeniyi, OJ, Adetimirin, VO, Asiedu, R, Ingelbrecht, Ivan   +3 more
core  

Axonal growth arrests after an increased accumulation of Schwann cells expressing senescence markers and stromal cells in acellular nerve allografts [PDF]

, 2016
Acellular nerve allografts (ANAs) and other nerve constructs do not reliably facilitate axonal regeneration across long defects (>3 cm). Causes for this deficiency are poorly understood.
Ee, Xueping, Hoben, Gwendolyn M, Hunter, Daniel A, Mackinnon, Susan E, Moore, Amy M, Pan, Deng, Poppler, Louis H, Schellhardt, Lauren, Snyder-Warwick, Alison K, Stewart, Sheila A, Wood, Matthew D, Yan, Ying   +11 more
core   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Loss and Reflection

Regeneration
A multimodal collaboration between artists, writers, and scholars. This piece emerged from an expedition to the Arctic archipelago as part of the Arctic Circle Residency in Autumn 2022.
Alexandra Lockhart, Andrea Legge, Dianne Chisholm, Drea Zlanabitnig, Hannah Larrabee   +4 more
doaj   +2 more sources

Re-expression of IGF-II is important for beta cell regeneration in adult mice [PDF]

, 2012
Background The key factors which support re-expansion of beta cell numbers after injury are largely unknown. Insulin-like growth factor II (IGF-II) plays a critical role in supporting cell division and differentiation during ontogeny but its role in the
David Epstein, Franco Folli, Hassan Nakhai, James Young, Julia Herold, Luxian Zhou, Michael Khan, Stella Pelengaris, Sylvie Abouna, Tim Wilhelm Nattkemper   +9 more
core   +3 more sources

Wildfires and climate change push low-elevation forests across a critical climate threshold for tree regeneration

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Changes in climate and disturbance regimes may cause abrupt shifts in vegetation communities. Identifying climatic conditions that can limit tree regeneration is important for understanding when and where wildfires may catalyze such changes.
K. Davis, S. Dobrowski, P. Higuera, Z. Holden, T. Veblen, Monica T. Rother, S. Parks, Anna Sala, M. Maneta   +8 more
semanticscholar   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Treadmill exercise prevents stress-induced anxiety-like behaviors via enhancing the excitatory input from the primary motor cortex to the thalamocortical circuit

Nature Communications
Physical exercise effectively prevents anxiety disorders caused by environmental stress. The neural circuitry mechanism, however, remains incomplete. Here, we identified a previously unrecognized pathway originating from the primary motor cortex (M1) to ...
Zhihua Luo, Junlin Chen, Yuchu Liu, Yelin Dai, Hui Gao, Borui Zhang, Haibin Ou, Kwok-Fai So, Ji-an Wei, Li Zhang   +9 more
doaj   +1 more source