Results 101 to 110 of about 2,200,062 (357)
Annual Review of Genetics, 2017 Understanding how and why animals regenerate complex tissues has the potential to transform regenerative medicine. Here we present an overview of genetic approaches that have recently been applied to dissect mechanisms of regeneration. We describe new advances that relate to central objectives of regeneration biologists researching different tissues ...
Chen-Hui, Chen, Kenneth D, Poss
openaire +2 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
A high-glucose diet affects Achilles tendon healing in rats
Scientific Reports, 2017 Chronic and acute tendinopathies are difficult to treat and tendon healing is generally a very slow and incomplete process and our general understanding of tendon biology and regeneration lags behind that of muscle or bone.
Stefanie Korntner +10 more
doaj +1 more source
Parental perspectives long term after neonatal clinical trial participation: a survey
Trials, 2020 Background Although recruiting newborns is ethically challenging, clinical trials remain essential to improve neonatal care. There is a lack of empirical data on the parental perspectives following participation of their neonate in a clinical trial ...
Thomas Salaets +8 more
doaj +1 more source
The human ARF tumor suppressor senses blastema activity and suppresses epimorphic tissue regeneration. [PDF]
, 2015 The control of proliferation and differentiation by tumor suppressor genes suggests that evolution of divergent tumor suppressor repertoires could influence species regenerative capacity.
Ahituv, Nadav +3 more
core +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
RegenerationA multimodal collaboration between artists, writers, and scholars. This piece emerged from an expedition to the Arctic archipelago as part of the Arctic Circle Residency in Autumn 2022.
Candace N Jensen +2 more
doaj +2 more sources
Learning partnerships : maximising the contribution of learning to local regeneration [PDF]
, 2003 "The aim of this study was to identify practice which can support Learning Partnerships (LPs) to develop their regeneration role. It also aims to help the Learning and Skills Council (LSC) to clarify how LPs can maximise the contribution of learning to ...
core
From area-based initiatives to strategic partnerships: have we lost the meaning of regeneration? [PDF]
, 2012 For forty years area-based initiatives (ABIs) were the primary tool used by UK governments to tackle problems of concentrated deprivation and dereliction.
Matthews, Peter
core +2 more sources
Fabrication of Scaffolds for Bone-Tissue Regeneration
Materials, 2019 The present article describes the state of the art in the rapidly developing field of bone tissue engineering, where many disciplines, such as material science, mechanical engineering, clinical medicine and genetics, are interconnected.
Petra Chocholata, V. Kulda, V. Babuška
semanticscholar +1 more source