Results 61 to 70 of about 1,641,482 (341)

On the side of the angels: community involvement in the governance of neighbourhood renewal. [PDF]

, 2005
This article draws upon the authors’ experiences of community-led regeneration developed while members of the National Evaluation Team for the NDC Programme.
Atkinson R., Civil Renewal Unit, Cochrane A., DETR, Fred Robinson, Gill Davidson, Henderson P., Imrie R., Keith Shaw, Mayo M., National Audit Office, Neighbourhood Renewal Unit, Neighbourhood Renewal Unit, NRU, NRU, ODPM, ODPM, Pearce G., Public Accounts Committee, Raco M., Shaw K., Social Exclusion Unit, Social Exclusion Unit   +22 more
core   +2 more sources

The various routes to functional regeneration in the central nervous system [PDF]

, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Echeverri, K.
Echeverri, Karen
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Treadmill exercise prevents stress-induced anxiety-like behaviors via enhancing the excitatory input from the primary motor cortex to the thalamocortical circuit

Nature Communications
Physical exercise effectively prevents anxiety disorders caused by environmental stress. The neural circuitry mechanism, however, remains incomplete. Here, we identified a previously unrecognized pathway originating from the primary motor cortex (M1) to ...
Zhihua Luo, Junlin Chen, Yuchu Liu, Yelin Dai, Hui Gao, Borui Zhang, Haibin Ou, Kwok-Fai So, Ji-an Wei, Li Zhang   +9 more
doaj   +1 more source

Wheel Running Improves Motor Function and Spinal Cord Plasticity in Mice With Genetic Absence of the Corticospinal Tract

Frontiers in Cellular Neuroscience, 2019
Our previous studies showed that mutant mice with congenital absence of the corticospinal tract (CST) undergo spontaneous remodeling of motor networks to partially compensate for absent CST function.
Wei Zhang, Bin Yang, Huandi Weng, Tao Liu, Lingling Shi, Panpan Yu, Kwok-Fai So, Yibo Qu, Libing Zhou, Libing Zhou, Libing Zhou   +10 more
doaj   +1 more source

Axonal regeneration in hippocampal and spinal cord organotypic slice cultures [PDF]

, 2010
Under normal conditions, axonal regeneration after lesions is not possible in mature CNS but can occur in embryonic and early postnatal nervous systems. In recent years, a number of possible strategies to enhance axonal regeneration and eventually treat ...
Bonnici, Brenda
core   +1 more source

A Regeneration Toolkit [PDF]

Developmental Cell, 2018
The ability of animals to replace injured body parts has been a subject of fascination for centuries. The emerging importance of regenerative medicine has reinvigorated investigations of innate tissue regeneration, and the development of powerful genetic tools has fueled discoveries into how tissue regeneration occurs.
Mayssa H, Mokalled, Kenneth D, Poss
openaire   +2 more sources

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

Advanced therapeutic scaffolds of biomimetic periosteum for functional bone regeneration

Journal of Nanobiotechnology
Treating chronic bone injuries and defects remains a significant challenge in orthopedic medicine, impacting patient mobility, recovery time, and healthcare costs.
Archita Gupta, Kyung Wook Kim, Amal George Kurian, Shreyas Kumar Jain, Suparna Bhattacharya, Rajendra K. Singh, Hae-Won Kim   +6 more
doaj   +1 more source