Results 61 to 70 of about 1,340,212 (344)
EMBO Molecular Medicine, 2011 AbstractThe death of cardiac myocytes diminishes the heart's pump function and is a major cause of heart failure, one of the dominant causes of death worldwide. Other than transplantation, there are no therapies that directly address the loss of cardiac myocytes, which explains the current excitement in cardiac regeneration.
Matthew L. Steinhauser +2 more
openaire +3 more sources
Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Molecular Oncology, EarlyView.Chen‐xi Li, Zhong‐cheng Gong
wiley +1 more source
Nature CommunicationsPhysical exercise effectively prevents anxiety disorders caused by environmental stress. The neural circuitry mechanism, however, remains incomplete. Here, we identified a previously unrecognized pathway originating from the primary motor cortex (M1) to ...
Zhihua Luo +9 more
doaj +1 more source
Seminars in Cell & Developmental Biology, 1999 @9cIntroduction@21T issues exhibit an impressive ability to respond to a myriad of insults by repairing and regenerating complex structures. The elegant and orderly process of regeneration provides clues to the mechanisms of pattern formation but also offers the hope that the process might one day be manipulated to replace damaged body parts.
H Theisen, H Theisen, J L Marsh
openaire +4 more sources
Journal of the American Academy of Orthopaedic Surgeons, 2013 Cartilage damaged by trauma has a limited capacity to regenerate. Current methods of managing small chondral defects include palliative treatment with arthroscopic débridement and lavage, reparative treatment with marrow-stimulation techniques (eg, microfracture), and restorative treatment, including osteochondral grafting and autologous chondrocyte ...
Rocky S, Tuan +2 more
openaire +2 more sources
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Stress increases hepatic release of lipocalin 2 which contributes to anxiety-like behavior in mice
Nature CommunicationsChronic stress induces anxiety disorders via both neural pathways and circulating factors. Although many studies have elucidated the neural circuits involved in stress-coping behaviors, the origin and regulatory mechanism of peripheral cytokines in ...
Lan Yan +9 more
doaj +1 more source
Systemic therapy of MSCs in bone regeneration: a systematic review and meta-analysis
Stem Cell Research & Therapy, 2021 Objectives Over the past decades, many studies focused on mesenchymal stem cells (MSCs) therapy for bone regeneration. Due to the efficiency of topical application has been widely dicussed and systemic application was also a feasible way for new bone ...
Jingfei Fu +5 more
doaj +1 more source
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor
Nature, 2018 Functional tissue regeneration is required for the restoration of normal organ homeostasis after severe injury. Some organs, such as the intestine, harbour active stem cells throughout homeostasis and regeneration; more quiescent organs, such as the lung,
W. Zacharias +8 more
semanticscholar +1 more source