Results 71 to 80 of about 1,397,234 (360)

Wheel Running Improves Motor Function and Spinal Cord Plasticity in Mice With Genetic Absence of the Corticospinal Tract

Frontiers in Cellular Neuroscience, 2019
Our previous studies showed that mutant mice with congenital absence of the corticospinal tract (CST) undergo spontaneous remodeling of motor networks to partially compensate for absent CST function.
Wei Zhang, Bin Yang, Huandi Weng, Tao Liu, Lingling Shi, Panpan Yu, Kwok-Fai So, Yibo Qu, Libing Zhou, Libing Zhou, Libing Zhou   +10 more
doaj   +1 more source

Ways of interpreting urban regeneration: Hamburg, London, Brussels and Rome [PDF]

, 2015
Over the coming decades all cities throughout and beyond Europe, be they large or small, will face the great challenge of regeneration. European Commission has promoted a “regeneration agenda” focused on an integrated sustainable approach. But, while the
Fratini, Fabiola
core   +1 more source

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

FEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma, Samar Kumar Basak, Sujata Das, Debasmita Pankaj Alone   +3 more
wiley   +1 more source

Regeneration of the heart

EMBO Molecular Medicine, 2011
AbstractThe death of cardiac myocytes diminishes the heart's pump function and is a major cause of heart failure, one of the dominant causes of death worldwide. Other than transplantation, there are no therapies that directly address the loss of cardiac myocytes, which explains the current excitement in cardiac regeneration.
Matthew L. Steinhauser, Richard T. Lee, Richard T. Lee   +2 more
openaire   +3 more sources

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

FEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya, Ksenia V. Sergeeva, Boris S. Shenkman, Timur M. Mirzoev   +3 more
wiley   +1 more source

Treadmill exercise prevents stress-induced anxiety-like behaviors via enhancing the excitatory input from the primary motor cortex to the thalamocortical circuit

Nature Communications
Physical exercise effectively prevents anxiety disorders caused by environmental stress. The neural circuitry mechanism, however, remains incomplete. Here, we identified a previously unrecognized pathway originating from the primary motor cortex (M1) to ...
Zhihua Luo, Junlin Chen, Yuchu Liu, Yelin Dai, Hui Gao, Borui Zhang, Haibin Ou, Kwok-Fai So, Ji-an Wei, Li Zhang   +9 more
doaj   +1 more source

Systemic therapy of MSCs in bone regeneration: a systematic review and meta-analysis

Stem Cell Research & Therapy, 2021
Objectives Over the past decades, many studies focused on mesenchymal stem cells (MSCs) therapy for bone regeneration. Due to the efficiency of topical application has been widely dicussed and systemic application was also a feasible way for new bone ...
Jingfei Fu, Yanxue Wang, Yiyang Jiang, Juan Du, Junji Xu, Yi Liu   +5 more
doaj   +1 more source

Exact Approach for Survivable Regenerator Placement in Translucent WDM Networks [PDF]

arXiv, 2017
Most studies addressing translucent network design targeted a trade-off between minimizing the number of deployed regenerators and minimizing the number of regeneration sites. The latter highly depends on the carrier's strategy and is motivated by various considerations such as power consumption, maintenance and supervision costs.
arxiv  

Iron role paradox in nerve degeneration and regeneration [PDF]

Bolandghamat, S., & Behnam-Rassouli, M. (2024). Iron role paradox in nerve degeneration and regeneration. Physiological Reports, 12, e15908
Iron accumulates in the neural tissue during peripheral nerve degeneration. Some studies have already been suggested that iron facilitates Wallerian degeneration (WD) events such as Schwann cell de-differentiation. On the other hand, intracellular iron levels remain elevated during nerve regeneration and gradually decrease.
arxiv   +1 more source

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

FEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei, Amir Barzegar Behrooz, Marco Cordani, Mahmoud Aghaei, Negar Azarpira, Daniel J. Klionsky, Saeid Ghavami   +6 more
wiley   +1 more source