Results 1 to 10 of about 180,038 (307)

Liver regeneration biology: Implications for liver tumour therapies. [PDF]

open access: yesWorld J Clin Oncol, 2021
The liver has remarkable regenerative potential, with the capacity to regenerate after 75% hepatectomy in humans and up to 90% hepatectomy in some rodent models, enabling it to meet the challenge of diverse injury types, including physical trauma, infection, inflammatory processes, direct toxicity, and immunological insults.
Hadjittofi C   +4 more
europepmc   +3 more sources

Flow Cytometry Characterization and Analysis of Glial and Immune Cells from the Spinal Cord

open access: yesNeuroglia
Several protocols have been developed with the aim of characterizing glial and immune cells from the central and peripheral nervous systems. However, a small number of these protocols have demonstrated the ability to yield satisfactory results following ...
Lilian de Oliveira Coser   +4 more
doaj   +1 more source

Ddx61-enriched condensates refine heart regeneration programs

open access: yesNature Communications
Gene regulatory mechanisms that underlie tissue regeneration have been largely studied at the level of transcription. Here, proximity labeling methods identify increased presence of the RNA helicase and P-body marker Ddx61 in adult zebrafish ...
Mira I. Pronobis   +6 more
doaj   +1 more source

Reconsidering regeneration in metazoans: an evo-devo approach

open access: yesFrontiers in Ecology and Evolution, 2015
Regeneration of body structures is an ability widely but unevenly distributed amongst the animal kingdom. Understanding regenerative biology in metazoans means understanding the multiplicity of the cellular and molecular mechanisms that lead to the ...
Stefano eTiozzo, Richard R Copley
doaj   +1 more source

The 29th Annual Meeting of the Society for Hard Tissue Regenerative Biology

open access: diamond, 2021
Hirohiko Okamura   +59 more
openalex   +2 more sources

Bioengineering strategies for regeneration of skin integrity: A literature review

open access: yesRegenerative Therapy
Objective: The skin is a complex organ that includes various stem cell populations. Current approaches for non-healing skin defects are sometimes inadequate and many attempts have been made to regenerate skin integrity.
Makoto Shiraishi   +4 more
doaj   +1 more source

DOT1L safeguards cartilage homeostasis and protects against osteoarthritis

open access: yesNature Communications, 2017
DOT1L is one of the few genes linked to osteoarthritis by human GWAS. Here the authors show that DOT1L-dependent histone methylation protects homeostasis of articular chondrocytes by SIRT1-dependent inhibition of canonical WNT signalling, and that ...
Silvia Monteagudo   +7 more
doaj   +1 more source

Use of Lectins to Enrich Mouse ES-Derived Retinal Progenitor Cells for the Purpose of Transplantation Therapy

open access: yesCell Transplantation, 2010
Using the mouse ES cell line with green fluorescent protein knocked-in at the Rx locus (Rx-KI ES cell), we previously showed that photoreceptors can be efficiently obtained in defined culture conditions by enriching Rx-positive retinal progenitor cells ...
Michiko Mandai   +5 more
doaj   +1 more source

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