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Cardiovascular Regeneration: Biology and Therapy [PDF]

Stem Cells International, 2017
Changwon Park, Kiwon Ban, Rebecca D. Levit, Wenbin Liang, Hun-Jun Park, Mary B. Wagner   +5 more
doaj   +6 more sources

Treatment response and several patient-reported outcomes are early determinants of future self-efficacy in rheumatoid arthritis

Arthritis Research & Therapy, 2021
Background Self-efficacy, or patients’ confidence in their ability to control disease and its consequences, was recently prioritised in EULAR recommendations for inflammatory arthritis self-management strategies. However, it remains unclear which factors
Doumen Michaël, De Cock Diederik, Pazmino Sofia, Bertrand Delphine, Joly Johan, Westhovens René, Verschueren Patrick   +6 more
doaj   +1 more source

Correction to: Treatment response and several patient-reported outcomes are early determinants of future self-efficacy in rheumatoid arthritis

Arthritis Research & Therapy, 2021
An amendment to this paper has been published and can be accessed via the original article.
Michaël Doumen, Diederik De Cock, Sofia Pazmino, Delphine Bertrand, Johan Joly, René Westhovens, Patrick Verschueren   +6 more
doaj   +1 more source

A novel retinal ganglion cell quantification tool based on deep learning

Scientific Reports, 2021
Glaucoma is a disease associated with the loss of retinal ganglion cells (RGCs), and remains one of the primary causes of blindness worldwide. Major research efforts are presently directed towards the understanding of disease pathogenesis and the ...
Luca Masin, Marie Claes, Steven Bergmans, Lien Cools, Lien Andries, Benjamin M. Davis, Lieve Moons, Lies De Groef   +7 more
doaj   +1 more source

MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System

Cells, 2021
Neuroinflammation has been put forward as a mechanism triggering axonal regrowth in the mammalian central nervous system (CNS), yet little is known about the underlying cellular and molecular players connecting these two processes.
Lien Andries, Luca Masin, Manuel Salinas-Navarro, Samantha Zaunz, Marie Claes, Steven Bergmans, Véronique Brouwers, Evy Lefevere, Catherine Verfaillie, Kiavash Movahedi, Lies De Groef, Lieve Moons   +11 more
doaj   +1 more source

Epithelial invagination by a vertical telescoping cell movement in mammalian salivary glands and teeth

Nature Communications, 2020
Mechanisms that regulate epithelial bending mainly link to cell shape changes, for example, the formation of wedge shaped cells. Here, the authors identify a different cell behaviour in the salivary glands and teeth where initial invagination arises by a
Jingjing Li, Andrew D. Economou, Barbara Vacca, Jeremy B. A. Green   +3 more
doaj   +1 more source

Effectiveness and feasibility of a mobile health self-management intervention in rheumatoid arthritis: study protocol for a pragmatic multicentre randomised controlled trial (AEGORA)

Trials, 2023
Background Rheumatoid arthritis (RA) considerably impacts patients’ lives. Patients’ confidence in their ability to manage this impact, or self-efficacy, can be supported with self-management interventions.
Michaël Doumen, Elias De Meyst, Cedric Lefevre, Sofia Pazmino, Johan Joly, Delphine Bertrand, Mieke Devinck, René Westhovens, Patrick Verschueren   +8 more
doaj   +1 more source

Characterization of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Cell Sheets Aiming for Clinical Application

Stem Cell Reports, 2014
Age-related macular degeneration (AMD) causes severe visual impairment due in part to age-dependent impairment of retinal pigment epithelium (RPE). It has been suggested that autologous human induced pluripotent stem cells (hiPSCs) may represent a useful
Hiroyuki Kamao, Michiko Mandai, Satoshi Okamoto, Noriko Sakai, Akiko Suga, Sunao Sugita, Junichi Kiryu, Masayo Takahashi   +7 more
doaj   +1 more source

Prior Exposure to Immunosuppressors Sensitizes Retinal Microglia and Accelerates Optic Nerve Regeneration in Zebrafish

Mediators of Inflammation, 2019
As adult mammals lack the capacity to replace or repair damaged neurons, degeneration and trauma (and subsequent dysfunction) of the central nervous system (CNS) seriously constrains the patient’s life quality.
Ilse Bollaerts, Jessie Van houcke, An Beckers, Kim Lemmens, Sophie Vanhunsel, Lies De Groef, Lieve Moons   +6 more
doaj   +1 more source

Neutrophil Chemotaxis and NETosis in Murine Chronic Liver Injury via Cannabinoid Receptor 1/Gα_i/o/ROS/p38 MAPK Signaling Pathway

Cells, 2020
Neutrophils play an essential role in the control of inflammatory diseases. However, whether cannabinoid receptors (CBs) play a role in neutrophil chemotaxis and NETosis in sterile liver inflammation remains unknown.
Xuan Zhou, Le Yang, Xiaoting Fan, Xinhao Zhao, Na Chang, Lin Yang, Liying Li   +6 more
doaj   +1 more source