Results 31 to 40 of about 1,689,985 (299)
Trials, 2023 Background Rheumatoid arthritis (RA) considerably impacts patients’ lives. Patients’ confidence in their ability to manage this impact, or self-efficacy, can be supported with self-management interventions.
Michaël Doumen +8 more
doaj +1 more source
Bioessays, 2020 Achieving regeneration of the central nervous system (CNS) is a major challenge for regenerative medicine. The inability of mammals to regrow a severed CNS contrasts with the amazing regenerative powers of their deuterostome kin, the echinoderms.
M. Byrne
semanticscholar +1 more source
Sex-dependent variation in cartilage adaptation: from degeneration to regeneration
Biology of Sex Differences, 2023 Despite acknowledgement in the scientific community of sex-based differences in cartilage biology, the implications for study design remain unclear, with many studies continuing to arbitrarily assign demographics. Clinically, it has been well-established
Jhanvee Patel +4 more
semanticscholar +1 more source
Peripheral Nerve Regeneration: Mechanism, Cell Biology, and Therapies [PDF]
BioMed Research International, 2014 Peripheral nerve injury has perplexed neuroscientists, neurologists, plastic surgeons, and bioengineers for decades. Despite the spontaneous ability of the adult peripheral nerve system to regenerate after injury, optimal and universal treatments capable of achieving full functional recovery are still unavailable.
Xiaofeng Jia +2 more
openaire +2 more sources
The role of roof plate-specific spondins in liver homeostasis and disease
Liver Research, 2022 As evolutionarily conserved signals, roof plate-specific spondins (R-spondins; RSPOs) are a family with four members (RSPO1–4) exerting distinctly different functions.
Le Yang +5 more
doaj +1 more source
Stem Cell Reports, 2014 Age-related macular degeneration (AMD) causes severe visual impairment due in part to age-dependent impairment of retinal pigment epithelium (RPE). It has been suggested that autologous human induced pluripotent stem cells (hiPSCs) may represent a useful
Hiroyuki Kamao +7 more
doaj +1 more source
PLoS ONE, 2010 The use of planarians as a model system is expanding and the mechanisms that control planarian regeneration are being elucidated. The planarian Schmidtea mediterranea in particular has become a species of choice.
Martin J. Blythe +10 more
semanticscholar +1 more source
Mediators of Inflammation, 2019 As adult mammals lack the capacity to replace or repair damaged neurons, degeneration and trauma (and subsequent dysfunction) of the central nervous system (CNS) seriously constrains the patient’s life quality.
Ilse Bollaerts +6 more
doaj +1 more source
Cells, 2020 Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication. With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the characteristics of producer cells, exosomes can be utilized as cell-free ...
D. Ha +11 more
semanticscholar +1 more source
Archives of Neurology, 1999 A few brief years ago, damage to the central nervous system was generally perceived to be irreparable, and loss of neurons was largely viewed as an irreversible process. However, major advances in the study of neural progenitor cells have altered these perceptions, and rational approaches to the repair of the damaged nervous system using transplanted ...
M F, Mehler, J A, Kessler
openaire +2 more sources