Results 31 to 40 of about 1,651,358 (339)

Effectiveness and feasibility of a mobile health self-management intervention in rheumatoid arthritis: study protocol for a pragmatic multicentre randomised controlled trial (AEGORA)

open access: yesTrials, 2023
Background Rheumatoid arthritis (RA) considerably impacts patients’ lives. Patients’ confidence in their ability to manage this impact, or self-efficacy, can be supported with self-management interventions.
Michaël Doumen   +8 more
doaj   +1 more source

The Link between Autotomy and CNS Regeneration: Echinoderms as Non-Model Species for Regenerative Biology.

open access: yesBioessays, 2020
Achieving regeneration of the central nervous system (CNS) is a major challenge for regenerative medicine. The inability of mammals to regrow a severed CNS contrasts with the amazing regenerative powers of their deuterostome kin, the echinoderms.
M. Byrne
semanticscholar   +1 more source

Sex-dependent variation in cartilage adaptation: from degeneration to regeneration

open access: yesBiology of Sex Differences, 2023
Despite acknowledgement in the scientific community of sex-based differences in cartilage biology, the implications for study design remain unclear, with many studies continuing to arbitrarily assign demographics. Clinically, it has been well-established
Jhanvee Patel   +4 more
semanticscholar   +1 more source

The role of roof plate-specific spondins in liver homeostasis and disease

open access: yesLiver Research, 2022
As evolutionarily conserved signals, roof plate-specific spondins (R-spondins; RSPOs) are a family with four members (RSPO1–4) exerting distinctly different functions.
Le Yang   +5 more
doaj   +1 more source

Progenitor Cell Biology [PDF]

open access: yesArchives of Neurology, 1999
A few brief years ago, damage to the central nervous system was generally perceived to be irreparable, and loss of neurons was largely viewed as an irreversible process. However, major advances in the study of neural progenitor cells have altered these perceptions, and rational approaches to the repair of the damaged nervous system using transplanted ...
John A. Kessler, Mark F. Mehler
openaire   +2 more sources

Characterization of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Cell Sheets Aiming for Clinical Application

open access: yesStem Cell Reports, 2014
Age-related macular degeneration (AMD) causes severe visual impairment due in part to age-dependent impairment of retinal pigment epithelium (RPE). It has been suggested that autologous human induced pluripotent stem cells (hiPSCs) may represent a useful
Hiroyuki Kamao   +7 more
doaj   +1 more source

Peripheral Nerve Regeneration: Mechanism, Cell Biology, and Therapies [PDF]

open access: yesBioMed Research International, 2014
Peripheral nerve injury has perplexed neuroscientists, neurologists, plastic surgeons, and bioengineers for decades. Despite the spontaneous ability of the adult peripheral nerve system to regenerate after injury, optimal and universal treatments capable of achieving full functional recovery are still unavailable.
Xiaofeng Jia   +2 more
openaire   +3 more sources

Wnt signaling in lung development, regeneration, and disease progression

open access: yesCommunications Biology, 2021
The respiratory tract is a vital, intricate system for several important biological processes including mucociliary clearance, airway conductance, and gas exchange.
Cody J. Aros   +2 more
semanticscholar   +1 more source

Prior Exposure to Immunosuppressors Sensitizes Retinal Microglia and Accelerates Optic Nerve Regeneration in Zebrafish

open access: yesMediators of Inflammation, 2019
As adult mammals lack the capacity to replace or repair damaged neurons, degeneration and trauma (and subsequent dysfunction) of the central nervous system (CNS) seriously constrains the patient’s life quality.
Ilse Bollaerts   +6 more
doaj   +1 more source

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