Results 51 to 60 of about 277,643 (298)

Carrier-envelope phase stabilization of a multi-millijoule, regenerative-amplifier-based chirped-pulse amplifier system

, 2009
This article reports on the successful stabilization of the carrier-envelope phase of a 1-kHz laser system that includes a large grating stretcher, a regenerative amplifier, a multipass amplifier and a grating compressor.
L'Huillier, Anne,, Persson, Anders,, Persson, Anders, Fordell, Thomas, L'Huillier, Anne, Fordell, Thomas,, Miranda, Miguel,, Lund University., Miranda, Miguel, M. Miranda, A. L'Huillier, A. Persson, T. Fordell   +12 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Simulations of the LANL regenerative amplifier FEL [PDF]

, 1997
The LANL regenerative amplifier FEL is designed to produce an average output power of 1 kW. Simulations study the transverse effects due to guiding by the intense electron beam and feedback. These simulations coupled with experimental measurements can be
Kesselring, M., Sheffield, R. L., Wong, R. K., Wong, R.K., Sheffield, R.L., Colson, W.B., Colson, W. B.   +6 more
core   +2 more sources

A 10-mJ-level regenerative amplifier based on an Yb:CaGdAlO4 single crystal with spectral shaping for gain narrowing suppression

High Power Laser Science and Engineering
In this work, we demonstrate a high-energy regenerative amplifier based on a single Yb:CaGdAlO4 (Yb:CALGO) crystal, delivering a pulse energy of 11.2 mJ at a 1 kHz repetition rate.
Fengchen Zhang, Yutong Zhang, Geyang Wang, Wenlong Tian, Yang Yu, Yishan Wang, Zhiyi Wei, Jiangfeng Zhu   +7 more
doaj   +1 more source

1 kHz, multi-mJ Yb:KYW bulk regenerative amplifier

, 2014
We report on a high energy Yb:KYW dual-crystal regenerative amplifier, delivering 6 mJ at 1 kHz. The pulses entered at 1030 nm, stretched with chirped fiber Bragg gratings, can sustain a sub-ps duration after ...
Kaertner, Franz, Anne-Laure Calendron, Calendron, Anne-Laure, Franz X. Kärtner, Cankaya, Huseyin, Huseyin Cankaya   +5 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Short wavelength regenerative amplifier free electron lasers [PDF]

, 2008
In this paper we discuss extending the operating wavelength range of tunable Regenerative Amplifier FELs to shorter wavelengths than current design proposals, notably into the XUV regions of the spectrum and beyond where the reflectivity of broadband ...
Thompson, N.R., McNeil, B W J, Dunning, D.J.   +2 more
core   +3 more sources

Multi-kHz, High Energy, Femtosecond Diode-Pumped Yb:CaF2 Regenerative Amplifier

, 2014
We report an efficient, high-energy, diode-pumped Yb:CaF2 regenerative amplifier. Energies up to 1.02 mJ at 1045-nm and 5 kHz-repetition rate in 324 fs-long pulses have been obtained with a beam quality factor of M2 =1 ...
M. Kemnitzer, AGNESI, ANTONIANGELO, Annalisa Guandalini, J. Aus der Au, PIRZIO, FEDERICO, Federico Pirzio, Matthias Kemnitzer, GUANDALINI, ANNALISA, Juerg Au der Au, E. Caracciolo, Etienne Caracciolo, Antonio Agnesi   +11 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

An x-ray regenerative amplifier free-electron laser using diamond pinhole mirrors

New Journal of Physics, 2019
X-ray free-electron lasers (FELs) rely on SASE due to the lack of seed lasers and the difficulty in obtaining mirrors. Progress in diamond crystal Bragg mirrors enables the design of x-ray FEL oscillators.
H P Freund, P J M van der Slot, Yu Shvyd’ko   +2 more
doaj   +1 more source