Results 101 to 110 of about 216,180 (312)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
On the effect of distributed regenerative delay on the stability lobe diagrams of milling processes [PDF]
, 2015 Regenerative machine tool chatter is investigated for milling operations with helical tools. The stability of a two-degrees-of-freedom milling model is analyzed, where the cutting-force is modeled as a force system distributed along the rake face of the ...
Molnár, Tamás G. +4 more
core +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Synergizing adaptive immunity and regenerative signals to enhance osteochondral defects repair
Bioactive MaterialsIn clinical practice, repairing osteochondral defects (OCDs) is challenging because of the complex cartilage/subchondral bone structure and intricate immunological microenvironment.
Changjian Lin +18 more
doaj +1 more source
Regenerative braking energy efficient synergistic utilization technology for AC electrified railways
机车电传动, 2022 Strengthening the research and application of regenerative braking energy utilization technology is an important measure to promote the low carbon development of AC electrified railways.
LYU Shunkai, ZHANG Min, ZHANG Zhixue
doaj
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Hydraulic hybrid regenerative braking [PDF]
, 2020 Capstone Project submitted to the Department of Engineering, Ashesi University in partial fulfillment of the requirements for the award of Bachelor of Science degree in Mechanical Engineering, May 2020Traditional friction brakes are wasteful in their ...
Ofori-Teiko, Joel Nana Yaw
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Effect of regenerative braking on energy-efficient train control
, 2015 An important topic to reduce the energy consumption in railways is the use of energy-efficient train control (EETC). Modern trains allow regen-erative braking where the released kinetic energy can be reused.
Scheepmaker, G.M. +3 more
core