Results 51 to 60 of about 216,180 (312)

Yb:CALYO-based femtosecond chirped pulse regenerative amplifier for temporally resolved pump-probe spectroscopy

open access: yesПриборы и методы измерений, 2018
Diode-pumped femtosecond chirped pulse regenerative amplifiers based on Yb3+-materials are of practical importance for wide range of scientific, industrial and biomedical applications.
A. S. Rudenkov   +5 more
doaj   +1 more source

Japan's challenges of translational regenerative medicine: Act on the safety of regenerative medicine

open access: yes, 2016
The first issue of Nature Medicine published 20 years ago featured an article that reported Japan's critical situation regarding clinical trials, calling for major reform.
Taoka, Masaomi   +5 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Periodontal surgery improves oral health-related quality of life in chronic periodontitis patients in Asian population

open access: yesKaohsiung Journal of Medical Sciences, 2017
The effect of periodontal surgery on patients' quality of life was investigated. Sixty patients received regenerative surgery or resective osseous surgery.
Yu-Hsiang Chou   +5 more
doaj   +1 more source

MODELLING AND ANALYSIS OF CHATTER MITIGATION STRATEGIES IN MILLING [PDF]

open access: yes, 2013
Machining stability plays a major role in improving machine tool performance and product quality. Uncontrolled chatter phenomenon causes too many defects and problems in manufacturing industry such as increased surface roughness, tool wear and even ...
Saleh, Khaled
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Multiphasic bone-ligament-bone integrated scaffold enhances ligamentization and graft-bone integration after anterior cruciate ligament reconstruction

open access: yesBioactive Materials
The escalating prevalence of anterior cruciate ligament (ACL) injuries in sports necessitates innovative strategies for ACL reconstruction. In this study, we propose a multiphasic bone-ligament-bone (BLB) integrated scaffold as a potential solution.
Xianrui Xie   +13 more
doaj   +1 more source

Heat transfer and flow structures of supercritical n-decane in a regenerative cooling channel loaded with non-uniform heat flux

open access: yesFrontiers in Energy Research, 2022
A harsh and complex thermal environment in the combustor threatens safe working of scramjets. In this study, heat transfer and flow structures of supercritical n-decane under 3 MPa in a regenerative cooling channel loaded with non-uniform heat flux ...
Jian Liu   +4 more
doaj   +1 more source

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