Results 61 to 70 of about 216,180 (312)

Regenerative effects of peptide nanofibers in an experimental model of Parkinson’s disease [PDF]

Acta Biomaterialia, 2016
Parkinson's disease (PD) is characterized by progressive degeneration of dopaminergic nigrostriatal neurons and reduction in striatal dopamine levels. Although there are few treatment options for PD such as Levodopa, they are used just to relieve and modify the symptoms.
Sever M., Turkyilmaz M., Sevinc C., Cakir A., Ocalan B., Cansev M., Guler M.O., Tekinay A.B.   +7 more
openaire   +6 more sources

Thermal Characteristics of Heating-furnace with Regenerative Burner [PDF]

, 2005
Thermal characteristics between the heating-furnace with regenerative burner and the classical triple-fired continuous furnace by heat balance testing for two billet steel heating-furnace at the same billet steel heating have been analyzed.
HUA, Jianshe, LI, Xiaoming, KAWABATA, Nobuyoshi   +2 more
core  

Hypoxic Culture Conditions as a Solution for Mesenchymal Stem Cell Based Regenerative Therapy [PDF]

, 2014
Cell-based regenerative therapies, based on in vitro propagation of stem cells, offer tremendous hope to many individuals suffering from degenerative diseases that were previously deemed untreatable.
Haque, N., Rahman, M. T., Alabsi, A. M., Abu Kasim, N. H.   +3 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Mechanically Derived Tissue Stromal Vascular Fraction Acts Anti-inflammatory on TNF Alpha-Stimulated Chondrocytes In Vitro [PDF]

, 2022
Enzymatically isolated stromal vascular fraction (SVF) has already shown to be effective as a treatment for osteoarthritis (OA). Yet, the use of enzymes for clinical purpose is highly regulated in many countries.
Joris A. van Dongen, Hieronymus P. Stevens, van Dongen, Joris A., Vonk, Lucienne A., van Boxtel, Joeri, Joeri van Boxtel, Stevens, Hieronymus P., Lucienne A. Vonk   +7 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Hypoxia and Foxn1 alter the proteomic signature of dermal fibroblasts to redirect scarless wound healing to scar-forming skin wound healing in Foxn1−/− mice

BMC Biology
Background Foxn1−/− deficient mice are a rare model of regenerative skin wound healing among mammals. In wounded skin, the transcription factor Foxn1 interacting with hypoxia-regulated factors affects re-epithelialization, epithelial-mesenchymal ...
Barbara Gawronska-Kozak, Sylwia Machcinska-Zielinska, Katarzyna Walendzik, Marta Kopcewicz, Mirva Pääkkönen, Joanna Wisniewska   +5 more
doaj   +1 more source

Impact of hydrogen fraction and operating parameters on a regenerative gas turbine's thermodynamic and emission behavior

Results in Engineering
Gas turbine power plants are essential to global energy production. This study presents a comprehensive analysis of the effects of hydrogen enrichment and regenerative cycles on the performance and emissions of gas turbines.
Abdalazeem Adam, Youssef Elmeknassi, Mohammednour Gibreel   +2 more
doaj   +1 more source