Tissue engineering is the science of design and manufacture of new tissues to replace impaired or damaged ones. The key ingredients for tissue engineering are stem cells, the morphogens, or growth factors that regulate their differentiation, and a scaffold of extracellular matrix that constitutes the microenvironment for their growth.
Rajnish K Singhal +5 more
openaire +2 more sources
Antibacterial TAP-mimic electrospun polymer scaffold: effects on P. gingivalis-infected dentin biofilm [PDF]
OBJECTIVES: This study sought to investigate, in vitro, the effects of a recently developed triple antibiotic paste (TAP)-mimic polymer nanofibrous scaffold against Porphyromonas gingivalis-infected dentin biofilm.
Albuquerque, Maria Tereza P. +4 more
core +2 more sources
Summary of: Regenerative endodontics [PDF]
Significant advances in our understanding of the biological processes involved in tooth development and repair at the cellular and molecular levels have underpinned the newly emerging area of regenerative endodontics. Development of treatment protocols based on exploiting the natural wound healing properties of the dental pulp and applying tissue ...
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Tatiana M. Botero, DDS, MS, Clinical Associate Professor, Department of Cariology, Restorative Sciences & Endodontics, School of Dentistry, University of Michigan, Ann Arbor, Michigan, USA [PDF]
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109588/1/etp12071_3 ...
Botero, Tatiana M.
core +1 more source
Dental regenerative therapy targeting sphingosine-1-phosphate (S1P) signaling pathway in endodontics
The establishment of regenerative therapy in endodontics targeting the dentin-pulp complex, cementum, periodontal ligament tissue, and alveolar bone will provide valuable information to preserve teeth.
Etsuko Matsuzaki +3 more
doaj +1 more source
Newer prospects of regenerative endodontics: A comprehensive and updated review of literature
In pediatric dental patients, the management of nonvital immature teeth with undeveloped root in endodontic practice pose difficult and cumbersome clinical situations or challenges for the dental practitioners owing to the various factors, namely, the ...
Mohammad Kamran Khan +1 more
doaj +1 more source
Pulp-dentin complex of immature permanent teeth can be damaged through microbial invasion caused by untreated tooth decay, trauma, and dental anomalies, consequently leading to pulp necrosis and incomplete root development without early intervention.
dos Reis-Prado, Alexandre Henrique +4 more
openaire +1 more source
Expert consensus on regenerative endodontic procedures
AbstractRegenerative endodontic procedures (REPs) is a biologic-based treatment modality for immature permanent teeth diagnosed with pulp necrosis. The ultimate objective of REPs is to regenerate the pulp-dentin complex, extend the tooth longevity and restore the normal function. Scientific evidence has demonstrated the efficacy of REPs in promotion of
Xi Wei +14 more
openaire +3 more sources
Assessment of the phenotypic effects of Platelet Rich Fibrin on Mesenchymal Stem Cells derived from Minced Pulp [PDF]
Our aim is to investigate the effects of autologous platelet-rich fibrin (PRF) on Mesenchymal Stem cell derived from Minced Pulp (MP-MSCs). We first developed a mouse model of PRF to study the phenotypic effects of PRF in cultured cells.
Shirodkar, Gautam
core
The Effect of Diluted Triple and Double Antibiotic Pastes on Dental Pulp Stem Cells and Established Enterococcus faecalis Biofilm [PDF]
Objectives To investigate the effect of various dilutions of antibiotic medicaments used in endodontic regeneration on the survival of human dental pulp stem cells (DPSCs) and to determine their antibacterial effect against established Enterococcus ...
Goebel, W. Scott +5 more
core +2 more sources

