Results 111 to 120 of about 376,416 (350)

Regenerative Medicine for Diabetes Mellitus

Cell Transplantation, 2009
In diabetes, a loss of pancreatic β-cells causes insulin dependency. When insulin dependency is caused by type 1 diabetes or pancreatic diabetes, for example, pancreatic β-cells need to be regenerated for definitive treatment.
Naoya Kobayashi M.D., Ph.D., Takeshi Yuasa, Teru Okitsu   +2 more
doaj   +1 more source

Esophagus and regenerative medicine

World Journal of Gastroenterology, 2012
In addition to squamous cell carcinoma, the incidence of Barrett's esophagus with high-grade dysplasia and esophageal adenocarcinoma is rapidly increasing worldwide. Unfortunately, the current standard of care for esophageal pathology involves resection of the affected tissue, sometimes involving radical esophagectomy.
Toshitaka Hoppo, Blair A. Jobe, Ricardo Londono, Stephen F. Badylak   +3 more
openaire   +3 more sources

Using a Supramolecular Approach to Engineer Modular Hydrogel Platforms for Culturing Protoplasts – from General Tissue Engineering to Cellular Agriculture

Advanced Biology, EarlyView.
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers, Erik J. Slootweg, Ferdinand C. O. Los, Patricia Y. W. Dankers   +3 more
wiley   +1 more source

The importance of detailed epigenomic profiling of different cell types within organs. [PDF]

, 2016
The human body consists of hundreds of kinds of cells specified from a single genome overlaid with cell type-specific epigenetic information. Comprehensively profiling the body's distinct epigenetic landscapes will allow researchers to verify cell types ...
Borok, Zea, Laird-Offringa, Ite A, Marconett, Crystal N, Stueve, Theresa Ryan, Zhou, Beiyun   +4 more
core   +1 more source

Nanocellulose Targets Regenerative Medicine

BioResources
The term “nanocellulose” encompasses a wide range of cellulose-derived nanomaterials, which are characterized by their diverse morphologies and chemical structures at the nanometer scale.
Takuya Kitaoka
doaj  

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

An in vitro mechanism study on the proliferation and pluripotency of human embryonic stems cells in response to magnesium degradation. [PDF]

, 2013
Magnesium (Mg) is a promising biodegradable metallic material for applications in cellular/tissue engineering and biomedical implants/devices. To advance clinical translation of Mg-based biomaterials, we investigated the effects and mechanisms of Mg ...
Liew, Chee Gee, Liu, Huinan, Nguyen, Thanh Yen   +2 more
core   +3 more sources

The role of platelet derived exosomes in regenerative medicine [PDF]

Nanomedicine Journal
Exosomes are a group of extracellular vesicles that are produced by various cells and are abundantly found in body fluids such as plasma. Due to their special structure, these small particles are able to carry and contain various compounds and establish ...
Seyyede Fatemeh Shams, Mohammadreza Javan, Faeze Shahriyari   +2 more
doaj   +1 more source

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

Advanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali, Mohamed H. Sherif, Nashwa Barakat, Bassant Yahia, Ahmed A. Shokeir, Basel Sitohy   +5 more
wiley   +1 more source

Cryopreservation Increases Availability and Usability of Ovine Adipose-tissue Derived Stem Cells for Regenerative Medicine Search [PDF]

, 2001
Ionela Movileanu, Klara Brînzaniuc, Marius Harpa, Ovidiu Simion Cotoi, Terezia Preda, Hussam Al Hussein, Horaţiu Suciu, Dan Simionescu   +7 more
openalex   +1 more source