Results 141 to 150 of about 3,835,856 (260)

Hybrid Biofabrication of a Hierarchically Organized Periosteum‐Inspired In Vitro Platform

Advanced Healthcare Materials, EarlyView.
A hybrid biofabrication strategy integrates melt electrowriting with extrusion‐based 3D bioprinting to create a hierarchically organized periosteum‐inspired in vitro platform. Spatially defined osteogenic, fibrous, and endothelial cell‐containing compartments support long‐term culture, osteogenic maturation, and CD31+ endothelial cell organization ...
Yakui Liu, Xinggui Tian, Anne Bernhardt, Anja Lode, Max von Witzleben, Ege Kirbas, Stefan Zwingenberger, Michael Gelinsky   +7 more
wiley   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

Regenerative medicine

Journal of Translational Medicine
Francisco Silva
doaj   +1 more source

Biocompatible Conjugated Electrospinning Nanofibrous Membrane With Self‐Powered Piezoelectric Capacity for Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
A self‐powered PCL/gelatin‐PVDF‐TrFE/MXene conjugated electrospun membrane integrates biocompatibility with enhanced piezoelectric responsiveness. Mechanical deformation is converted into localized electrical signals that stimulate wound‐repair cells proliferation and migration, promote angiogenesis and tissue remodeling, and accelerate full‐thickness ...
Diandian Li, Ke Wu, Yangyang Lu, Qinglan Xia, Jialong Chen, Yifan Zhang, Zhaoyu Chen, Zhiyuan She, Junjin Jie, Juzi Xia, Muran Zhou, Aimei Zhong   +11 more
wiley   +1 more source

Fabrication of Aligned Polycaprolactone Nanofibrillar Bundles to Control Cell‐Mediated Collagen Deposition in Engineered Cartilage

Advanced Materials, EarlyView.
Melt electrofibrillation (MEF) enables the fabrication of nanofibrillar PCL scaffolds with defined architectures that guide cellular alignment and retention during cartilage tissue engineering. Unlike conventional melt electrowriting, MEF consistently directs collagen type II‐rich extracellular matrix organization, providing a tunable platform to ...
Alba Pueyo Moliner, Lennard Spauwen, James L. Martin Robinson, Ángela García Grech, Isabelle Martinier, Sara Grasselli, Aylin Kara Özenler, Matthias Ryma, Jürgen Groll, Mylène de Ruijter, Jos Malda   +10 more
wiley   +1 more source

RNA therapeutics for regenerative medicine

It is estimated that millions of people around the world experience various types of tissue injuries every year. Regenerative medicine was born and developed for understanding and application with the aim of replacing affected organs or some cells.
Lin S.-C., Chu D.-T., Nguyen Thi Y.V., Ngo A.D., Wu C.-C.   +4 more
core   +1 more source

Biohybrid Crawling Robot With Spiral‐Spring Backbone and Inclined Legs for Enhanced Locomotion

Advanced Materials, EarlyView.
We present a biohybrid crawling robot integrating a muscle ring with a flexible skeleton combining two complementary structural elements. The spiral‐spring backbone enables large‐amplitude bending without compromising axial stability, while outward‐inclined legs with unequal front–rear lengths effectively convert deformation into directional strides ...
Tomohiro Morita, Minghao Nie, Shoji Takeuchi   +2 more
wiley   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Vitamin C‐Induced Photo‐Redox Threshold Enables High‐Fidelity Volumetric Printing of Collagen

Advanced Materials, EarlyView.
Tomographic volumetric printing (TVP) of native proteins is limited by uncontrolled background crosslinking. Here, vitamin C is introduced as a biocompatible redox regulator to establish a tunable nonlinear polymerization threshold response for TVP.
Bin Wang, Amelia Hasenauer, Kristian Ivkovic, Ann‐Sophie Frind, David Fercher, Marcy Zenobi‐Wong   +5 more
wiley   +1 more source

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

Advanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye, Xuanzhe Liu, Zifan Pei, Chenyi Jiang, Xiaofen Zhang, Lin Lin, Qihang Fang, Binyu Chen, Longxiang Shen, Liang Cheng, Peng Ding, Xianyou Zheng   +11 more
wiley   +1 more source