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Regenerative Therapy, 2016 Recently, regenerative medicine has become a highlighted field because it has great potential to induce a paradigm shift of supportive conventional therapy into definitive treatment. The cornea is the avascular, transparent, dome-shaped outermost layer of the eyeball, and it consists of three layers: epithelium, stroma, and endothelium.
Yoshinori Oie, Kohji Nishida
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Designing stem cell niches for differentiation and self-renewal [PDF]
, 2018 Mesenchymal stem cells, characterized by their ability to differentiate into skeletal tissues and self-renew, hold great promise for both regenerative medicine and novel therapeutic discovery. However, their regenerative capacity is retained only when in
Dalby, Matthew J. +2 more
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Therapeutic Potential of Mesenchymal Stem Cells for Cancer Therapy [PDF]
, 2020 Mesenchymal stem cells (MSCs) are among the most frequently used cell type for regenerative medicine. A large number of studies have shown the beneficial effects of MSC-based therapies to treat different pathologies, including neurological disorders ...
Capilla González, Vivian +4 more
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Regenerative Medicine in Diabetes [PDF]
Mayo Clinic Proceedings, 2015 Diabetes is a common multisystem disease that results in hyperglycemia due to a relative or absolute insulin deficiency. Improved glycemic control decreases the risk of development and progression of microvascular and, to a lesser extent, macrovascular complications and prevents symptomatic hyperglycemia.
Adrian Vella, Aleksey V. Matveyenko
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Regenerative medicine: going beyond transplantology
Infusion & Chemotherapy, 2022 Since the possibilities of transplantology are limited, there is a need for tissue engineering and regenerative medicine (RM). Several high-tech approaches are used in RM: the use of soluble molecules, gene therapy, stem cell transplantation, tissue ...
M.I. Gumeniuk
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A roadmap for regenerative medicine [PDF]
Current Biology, 2012 SummaryUK research councils have drawn up a strategic plan for the development of regenerative medicine, covering all aspects from basic research through to commercialisation. Michael Gross reports.
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Potential use of human periapical cyst-mesenchymal stem cells (hPCy-MSCs) as a novel stem cell source for regenerative medicine applications [PDF]
, 2017 Mesenchymal stem cells (MSCs) are attracting growing interest by the scientific community due to their huge regenerative potential. Thus, the plasticity of MSCs strongly suggests the utilization of these cells for regenerative medicine applications.
Codispoti, Bruna +6 more
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Nanosensors for Regenerative Medicine
Journal of Biomedical Nanotechnology, 2014 Assessing biodistribution, fate, and function of implanted therapeutic cells in preclinical animal experiments is critical to realize safe, effective and efficient treatments for subsequent implementation within the clinic. Currently, tissue histology, the most prevalent analytical technique to meet this need, is limited by end-point analysis, high ...
Yeo, David C. +3 more
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Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids [PDF]
, 2019 Tissue specific extracellular matrices (ECM) provide structural support and enable access to molecular signals and metabolites, which are essential for directing stem cell renewal and differentiation.
Al-Aama, Jumana +15 more
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Brazilian Archives of Biology and Technology, 2022 The use of Wharton's Jelly (WJ) as a biomaterial is currently undergoing an appearance in the regenerative medicine field. The biomaterials applications focus on the aspects of cellular growth or delivery of proteins capable of stimulating cellular ...
Luize Kremer Gamba +10 more
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