Results 141 to 150 of about 293,878 (305)

Map Intersection Based Merging Schemes for Administrative Data Sources and an Application to Germany [PDF]

In many situations the applied researcher wants to combine different data sources without knowing the exact link and merging rule. This paper introduces a theoretical framework how two different regional administrative data sources can be merged.
Arntz, Melanie, Wilke, Ralf A.
core  

Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells

Advanced Science, EarlyView.
Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale, Luca Messina, Valeria Panzetta, Stefania Saporito, Costantino Menna, Maurizio Ventre, Paolo A. Netti   +6 more
wiley   +1 more source

Area interpolation in presence of measurement error and an application to German administrative data [PDF]

"In many situations the applied researcher wants to combine different data sources without knowing the exact link and merging rule. This paper considers different interpolation methods for interpolating attributes from German labor office districts to ...
Arntz, Melanie, Wilke, Ralf A.
core  

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang, Rong Ren, Zhan Su, Jiahao Zhou, Pinyin Cao, Sicheng Zhang, Zhen Li, Chao Li, Songsong Zhu   +8 more
wiley   +1 more source

Examining Brain Function Changes in HIV‐Infected Patients With Asymptomatic Neurocognitive Impairment: A Longitudinal Study

Brain and Behavior
Background HIV‐associated neurocognitive disorders (HAND), especially asymptomatic neurocognitive impairment (ANI), the initial stage of HAND, persist among a substantial proportion of individuals living with HIV despite the introduction of combination ...
Juming Ma, Zhongkai Zhou, Shuai Han, Chuanke Hou, Xingyuan Jiang, Fan Xu, Haixia Luo, Jiaojiao Liu, Wei Wang, Haiyan Zhao, Lingling Zhao, Hongjun Li   +11 more
doaj   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

Regional homogeneity and functional connectivity of freezing of gait conversion in Parkinson's disease. [PDF]

Front Aging Neurosci, 2023
Bao Y, Ya Y, Liu J, Zhang C, Wang E, Fan G.   +5 more
europepmc   +1 more source

Regional frequency analysis for mapping drought events in north-central Chile [PDF]

, 2011
Cornelis, Wim, Morales, Luis, Núñez, Jorge H, Schaefer, Mel G, Verbist, Koen, Wallis, Jim R   +5 more
core   +1 more source