Results 81 to 90 of about 84,741 (268)

Modelling fatalities on regional road networks

MATEC Web of Conferences, 2017
During the last decade Poland’s road fatalities went down by 44%. The trend differs from region to region. Effective road safety management in regions requires tools for forecasting road safety measures and identifying factors influencing road fatality ...
Wachnicka Joanna
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A Comprehensive Strategy for Activated Sludge Wastewater Treatment Facilities for Nutrient Removal Treatment [PDF]

BIO Web of Conferences
Traditional wastewater processing systems employ techniques that require a very lot of energy, so we need to get creative about doing that better and more sustainable.
Ihouaten Abderrazzak, El-Moustaqim Khadija, Abarkan Ahmed, Azoulay Karima, Lamchaimech Aziza, Moufti Ahmed, Mabrouki Jamal   +6 more
doaj   +1 more source

Model of Sustainable Development of the Region

Mediterranean Journal of Social Sciences, 2014
© MCSER-Mediterranean Center of Social and Educational Research. Assessment and analysis of the main characteristics of the socio-economic development of regions are among the most important ones that allow to solve strategic issues of the choice of optimal solutions in the sphere of regional governance and development prospects.
Gabdrakhmanov N., Rubtzov V., Mustafin M., Pratchenko O.   +3 more
openaire   +4 more sources

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Localized assessment of urban forest structures with 3D indicators

Ecological Indicators
Urban trees, as nature-based solutions, are crucial for climate change adaptation, biodiversity, and human well-being. Although heterogeneous vertical structures are inherent to urban spaces, decisions on tree preservation and planting often rely on 2D ...
Markus Münzinger, Dirk Burghardt, Martin Behnisch   +2 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Modelling and Forecasting Regional Growth: The MASST Model

, 2020
Among the vast number of regional growth forecasting models, the past 15 years witnessed the emergence of the MAcroeconomic, Sectoral, Social, Territorial (MASST) model. The MASST model aims at merging macroeconomic elements with territorial features for forecasting regional growth trajectories.
Capello R, Caragliu A
openaire   +3 more sources

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source