Results 31 to 40 of about 8,931,171 (392)

Firm evolution and cluster specialization: a social network analysis of resource industry change in two Australian cities

open access: yesRegional Studies, Regional Science, 2018
Evolutionary perspectives have been increasingly applied to understanding industry agglomeration. By tracking change over time, evolutionary perspectives shed a light on firm-level and sectoral changes that are contextualized within global industrial ...
Glen Searle   +2 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Book Review: Peter Batey, David Plane (Editors), Great Minds in Regional Science (Vol.2), Springer, 2023 [PDF]

open access: yesRomanian Journal of Regional Science
The subseries Great Minds in Regional Science, along with the subseries The Voice of Regional Science, comprise the book series titled Footprints in Regional Science, published under The Regional Science Academy.
Christa D. Court
doaj   +1 more source

Book review Development of paradigmatic ideas in the domestic regional economics by Evgeny Animitsa et al.

open access: yesJournal of New Economy, 2023
The paper presents an overview of a monograph prepared by a team of scholars representing the Ural school of regional economics, which was created under the leadership of Evgeny Animitsa and is based in the Ural State University of Economics ...
Olga N. Buchinskaia
doaj   +1 more source

Regional surname affinity: a spatial network approach [PDF]

open access: yes, 2019
OBJECTIVE We investigate surname affinities among areas of modern‐day China, by constructing a spatial network, and making community detection.
Chen, Jiawei   +5 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

SCIENCE-POLICY INTERFACE IN REGIONAL ENVIRONMENTAL MANAGEMENT: CASE OF HELCOM IN THE BALTIC CONTEXT

open access: yesСоціальна економіка, 2023
The regional environmental cooperation in the Baltic Sea is the leading and “forerunner” model for managing environmental challenges at the regional level.
Uyanga Tsenddorj, Buyandelger Doljin
doaj   +1 more source

Home - About - Disclaimer - Privacy