Results 41 to 50 of about 3,300,692 (345)

Regional Science in a time of uncertainty

REGION, 2016
I have given this paper the title  ‘Regional Science in a time of uncertainty’ because that is what it appears to be,  very much a time of uncertainty. Uncertainty is always with us, but what I mean is the future is more uncertain than usual.
Bernard Fingleton
doaj   +1 more source

Council of the Baltic Sea States: The Role of a Sustainable and Prosperous Region in Bringing Science Diplomacy Forward. EL-CSID Working Paper Issue 2018/19 • July 2018 [PDF]

, 2018
2017 has been a year full of promising major milestones for the future EU Science Diplomacy Strategy. At the beginning of 2017, the Directorate-General for Research and Innovation (DG RTD) of the European Commission released a thought-provoking report ...
Šime, Zane
core  

Regional surname affinity: a spatial network approach [PDF]

, 2019
OBJECTIVE We investigate surname affinities among areas of modern‐day China, by constructing a spatial network, and making community detection.
Chen, Jiawei, Li, Le, Shi, Yongbin, Stanley, H. Eugene, Wang, Yougui, Yuan, Yida   +5 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Contemporary Regional Studies – Theory, Methodology and Practice

Studia Regionalne i Lokalne, 2006
The paper offers a review of the evolution in defining and describing regions, showing mutual relationships between particular approaches and logical succession between various analytical concepts of the region.
Iwona Sagan
doaj  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Contemporary Seismicity in and Around the Yakima Fold-and-Thrust Belt in Eastern Washington [PDF]

, 2012
We examined characteristics of routinely cataloged seismicity from 1970 to the present in and around the Yakima fold-and-thrust belt (YFTB) in eastern Washington to determine if the characteristics of contemporary seismicity provide clues about regional ...
Burns, E., Gomberg, J., Sherrod, B., Snyder, D., Trautman, M.   +4 more
core   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Terminological Traps for Russian Bilingual Scientists

Polylinguality and Transcultural Practices
This study addresses the issue of terminological pitfalls encountered by Russian bilingual scholars working in the field of linguoculturology and other humanities disciplines.
Chimiza K. Lamazhaa
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source