Results 41 to 50 of about 3,173,534 (349)

Contemporary Seismicity in and Around the Yakima Fold-and-Thrust Belt in Eastern Washington [PDF]

open access: yes, 2012
We examined characteristics of routinely cataloged seismicity from 1970 to the present in and around the Yakima fold-and-thrust belt (YFTB) in eastern Washington to determine if the characteristics of contemporary seismicity provide clues about regional ...
Burns, E.   +4 more
core   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Core-Periphery and Peripherality in Regional Science [PDF]

open access: yesProstranstvennaâ Èkonomika
The article presents an analytical review of the development of the core-periphery and peripherality concepts in economic theory. The stages of formation of the core-periphery approach are marked by the contributions of the school of Latin American ...
Larisa Victorovna Melnikova
doaj   +1 more source

Concentración y desigualdad científica en América Latina y el Caribe a principios del siglo XXI: un estudio cienciométrico = Scientific concentration and inequality in Latin America and the Caribbean at the beginning of the 21st century: A scientometric study

open access: yesInformación, Cultura y Sociedad, 2020
La región de América Latina y el Caribe es amplia, diversa y desigual, incluso en la ciencia y en la tecnología. Este artículo analiza la concentración de insumos y resultados científicos y discute aspectos de la desigualdad en la ciencia regional. Es un
Dirce Maria Santin   +1 more
doaj   +1 more source

SCIENCE-POLICY INTERFACE IN REGIONAL ENVIRONMENTAL MANAGEMENT: CASE OF HELCOM IN THE BALTIC CONTEXT

open access: yesСоціальна економіка, 2023
The regional environmental cooperation in the Baltic Sea is the leading and “forerunner” model for managing environmental challenges at the regional level.
Uyanga Tsenddorj, Buyandelger Doljin
doaj   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

A Study on Green Economy Indicators and Modeling: Russian Context [PDF]

open access: yes, 2019
This article aims to assess and forecast the dynamics of a regional green economy. The research relevance is determined by the need to develop theoretical and methodological basis of the green economy for the transition period and to identify criteria ...
Drozhzhin, A.   +4 more
core   +2 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Advances in Teaching & Learning Day Abstracts 2005 [PDF]

open access: yes, 2004
Proceedings of the Advances in Teaching & Learning Day Regional Conference held at The University of Texas Health Science Center at Houston in ...
Phelps, Cynthia L.
core   +3 more sources

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy