Results 61 to 70 of about 3,106,115 (349)
La región de América Latina y el Caribe es amplia, diversa y desigual, incluso en la ciencia y en la tecnología. Este artículo analiza la concentración de insumos y resultados científicos y discute aspectos de la desigualdad en la ciencia regional. Es un
Dirce Maria Santin+1 more
doaj +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source
Council of the Baltic Sea States: The Role of a Sustainable and Prosperous Region in Bringing Science Diplomacy Forward. EL-CSID Working Paper Issue 2018/19 • July 2018 [PDF]
2017 has been a year full of promising major milestones for the future EU Science Diplomacy Strategy. At the beginning of 2017, the Directorate-General for Research and Innovation (DG RTD) of the European Commission released a thought-provoking report ...
Šime, Zane
core
The environment in regional science: An eclectic review [PDF]
The environment, broadly construed, is increasingly a salient topic in regional science research. Theoretical and empirical inquiries by regional scientists have progressively begun to address the manifold environmental ramifications of regional science questions.
Peter Nijkamp+2 more
openaire +3 more sources
Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases
FEBS Letters, EarlyView.
Igor Zivkovic+2 more
wiley +1 more source
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková+14 more
wiley +1 more source
Planning and Regional Science [PDF]
Always prone to introspection and self-criticism, academic planners have been confessing recently that what occurs in the halls of academe may be unresponsive and irrelevant to the real life of planners. If the discipline of planning is tangential to the profession of planning, what role can regional science be expected to play?
openaire +2 more sources
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Regional surname affinity: a spatial network approach [PDF]
OBJECTIVE We investigate surname affinities among areas of modern‐day China, by constructing a spatial network, and making community detection.
Chen, Jiawei+5 more
core +1 more source