Results 61 to 70 of about 3,060,494 (349)

Concentración y desigualdad científica en América Latina y el Caribe a principios del siglo XXI: un estudio cienciométrico = Scientific concentration and inequality in Latin America and the Caribbean at the beginning of the 21st century: A scientometric study

Información, Cultura y Sociedad, 2020
La región de América Latina y el Caribe es amplia, diversa y desigual, incluso en la ciencia y en la tecnología. Este artículo analiza la concentración de insumos y resultados científicos y discute aspectos de la desigualdad en la ciencia regional. Es un
Dirce Maria Santin, Sônia Elisa Caregnato   +1 more
doaj   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

The environment in regional science: An eclectic review [PDF]

Papers in Regional Science, 2003
The environment, broadly construed, is increasingly a salient topic in regional science research. Theoretical and empirical inquiries by regional scientists have progressively begun to address the manifold environmental ramifications of regional science questions.
Peter Nijkamp, Peter Nijkamp, Amitrajeet A. Batabyal   +2 more
openaire   +3 more sources

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

FEBS Letters, EarlyView.
Igor Zivkovic, Morana Dulic, Ita Gruic‐Sovulj   +2 more
wiley   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Współczesne studia regionalne – teoria i metodologia, a także praktyka

Studia Regionalne i Lokalne, 2004
Artykuł podejmuje próbę przekrojowego przedstawienia ewolucji sposobów definiowania i opisu regionów, wskazując na ich wzajemne wynikanie oraz logiczne następstwo kolejnych analitycznych koncepcji regionu.
Iwona Sagan
doaj  

Genetic diversity and population structure of the Taigan dog breed

FEBS Open Bio, EarlyView.
The Taigan is a rare sighthound from the mountains of Kyrgyzstan. We used DNA markers to study its genetic diversity and compare it with other sighthound breeds. Our findings show that the Taigan shares close genetic ties with the Kazakh Tazy, suggesting a common ancestry shaped by nomadic traditions and regional adaptation.
Kira Bespalova, Anastassiya Perfilyeva, Мamura Begmanova, Assel Zhaxylykova, Arailym Yerzhan, Kanagat Yergali, Almazbek Akunov, Marat Munarbek uulu, Anna Khamchukova, Almira Amirgaliyeva, Yelena Kuzovleva   +10 more
wiley   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

A Comparison of U. S. and European University-Industry Relations in the Life Sciences [PDF]

, 2002
We draw on diverse data sets to compare the institutional organization of upstream life science research across the United States and Europe. Understanding cross-national differences in the organization of innovative labor in the life sciences requires ...
Arora A., Batagelj V., Ben-David J., Fabio Pammolli, Geiger R., Greenacre M. J., Greenacre M. J., Guyon X., Guyon X., Jason Owen-Smith, Massimo Riccaboni, Morange M., Mowery D., Orsenigo L., Owen-Smith J., Pammolli F., Pavitt K., Peterson J., Stokes D. E., Walter W. Powell, Winkler G., Zucker L. G.   +21 more
core   +3 more sources