Results 51 to 60 of about 45,110,513 (323)

Thirty Years of Regional Climate Modeling: Where Are We and Where Are We Going next?

open access: yesJournal of Geophysical Research: Atmospheres, 2019
The year 2019 marks the thirtieth anniversary of the development of the first regional climate model (RCM), and here an overview is provided of the progress in regional modeling research and of the main challenges lying ahead.
F. Giorgi
semanticscholar   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

ФОРМИРОВАНИЕ СИБИРСКОЙ ИДЕНТИЧНОСТИ У СТУДЕНТОВ-ГЕОГРАФОВ (НА ПРИМЕРЕ УЧЕБНЫХ ДИСЦИПЛИН «ЭКОНОМИЧЕСКАЯ И СОЦИАЛЬНАЯ ГЕОГРАФИЯ ЗАПАДНО-СИБИРСКОГО РАЙОНА», «КРАЕВЕДЕНИЕ» И «ТОПОНИМИКА»)

open access: yesНаучно-педагогическое обозрение, 2019
Исследования были посвящены разработке содержания дисциплин «Экономическая и социальная география Западно-Сибирского района», «Краеведение» и «Топонимика», преподаваемых в Томском государственном педагогическом университете. Выявлены наиболее эффективные
Ершова Татьяна Владимировна   +1 more
doaj   +1 more source

Exploring firm performance in Central and Eastern European regions: a foundational approach

open access: yesHungarian Geographical Bulletin, 2023
Economic development in post-transition countries is dominated by the performance of capital cities, although second-tier cities are also important drivers of development.
Ildikó Egyed, Zsuzsanna Zsibók
doaj   +1 more source

Towards a comprehensive understanding of new regional industrial path development

open access: yesRegional studies, 2019
Path creation is a key concept in economic geography. So far, particularly scholars within evolutionary economic geography have pioneered research on this topic.
R. Hassink, A. Isaksen, Michaela Trippl
semanticscholar   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Towards research impact: using place-based policy to develop new research methods for bridging the academic/policy divide

open access: yesRegional Studies, Regional Science, 2020
There is increasing pressure on academics to show the impact of their research. At the same time, policy-makers are expected to draw upon a wide base of evidence, including academic research, to develop innovative solutions to often intractable societal ...
Fiona McKenzie   +4 more
doaj   +1 more source

Eurasian Regionalism as a Research Agenda. Interview with Dr. Mikhail A. Molchanov, University of Salamanca, Spain

open access: yesVestnik RUDN. International Relations, 2020
Mikhail Aleksandrovich Molchanov is a prominent Canadian political scholar, professor and publicist. He has worked as a senior policy analyst for the Government of Canada and a professor of political science at several Canadian universities.
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doaj   +1 more source

The Torockó Myth. Notions to the Sociographic Interpretation of Heritage Space [PDF]

open access: yesBelvedere Meridionale, 2014
The paper shows the development of a myth about Torockó in the literary works (fiction and scientific literature as well). The analysis follows the myth from its foundation in the 19th century to the second half of the 20th century.
TAMÁSKA, Máté
doaj   +1 more source

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