Results 31 to 40 of about 45,362 (276)

Elucidation of hemilabile-coordination-induced tunable regioselectivity in single-site Rh-catalyzed heterogeneous hydroformylation

Nature Communications
Revealing key factors that modulate the regioselectivity in heterogeneous hydroformylation requires identifying and monitoring the dynamic evolution of the truly active center under real reaction conditions. However, unambiguous in situ characterizations
Benhan Fan, Miao Jiang, Guoqing Wang, Yang Zhao, Bingbao Mei, Jingfeng Han, Lei Ma, Cunyao Li, Guangjin Hou, Tao Wu, Li Yan, Yunjie Ding   +11 more
doaj   +1 more source

Exploring the Potential of Cytochrome P450 CYP109B1 Catalyzed Regio—and Stereoselective Steroid Hydroxylation

Frontiers in Chemistry, 2021
Cytochrome P450 enzyme CYP109B1 is a versatile biocatalyst exhibiting hydroxylation activities toward various substrates. However, the regio- and stereoselective steroid hydroxylation by CYP109B1 is far less explored.
Xiaodong Zhang, Yun Hu, Wei Peng, Chenghua Gao, Qiong Xing, Binju Wang, Aitao Li   +6 more
doaj   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

Identify Regioselective Residues of Ginsenoside Hydrolases by Graph-Based Active Learning from Molecular Dynamics

Molecules
Identifying the catalytic regioselectivity of enzymes remains a challenge. Compared to experimental trial-and-error approaches, computational methods like molecular dynamics simulations provide valuable insights into enzyme characteristics.
Yi Li, Hong-Qian Peng, Meng-Liang Wen, Li-Quan Yang   +3 more
doaj   +1 more source

Relative Strength of Common Directing Groups in Palladium-Catalyzed Aromatic C−H Activation

iScience, 2019
Summary: Efficient functionalization of C−H bonds can be achieved using transition metal catalysts, such as Pd(OAc)2. To better control the regioselectivity in these reactions, some functional groups on the substrate may be used as directing groups ...
Anna Tomberg, Michael Éric Muratore, Magnus Jan Johansson, Ina Terstiege, Christian Sköld, Per-Ola Norrby   +5 more
doaj   +1 more source

Azaporphyrinoid‐Based Photo‐ and Electroactive Architectures for Advanced Functional Materials

Advanced Materials, EarlyView.
A long‐standing collaboration between the Torres and Guldi groups has yielded diverse azaporphyrinoid‐based donor‐acceptor nanohybrids with promising applications in solar energy conversion. This conspectus highlights key molecular platforms and structure‐function relationships that govern light and charge management, supporting the rational design of ...
Jorge Labella, Kobra Azizi, Dirk M. Guldi, Tomás Torres   +3 more
wiley   +1 more source

Regio‐ and enantioselective nickel-alkyl catalyzed hydroalkylation of alkynes

Nature Communications
The migratory insertion of metal-hydride into alkene has allowed regioselective access to organometallics, readily participating in subsequent functionalization as one conventional pathway of hydroalkylation, whereas analogous process with feedstock ...
Qian Gao, Wei-Cheng Xu, Xuan Nie, Kang-Jie Bian, Hong-Rui Yuan, Wen Zhang, Bing-Bing Wu, Xi-Sheng Wang   +7 more
doaj   +1 more source

Semi-rational engineering of an α-L-fucosidase for regioselective synthesis of fucosyl-N-acetylglucosamine disaccharides

Food Chemistry: Molecular Sciences
α-L-Fucosidases are attractive biocatalysts for the production of bioactive fucosylated oligosaccharides, however, poor regioselectivity and activity for transglycosylation have significantly limited their applications.
Peng Liu, Xiaodi Chen, Xueting Cao, Yuying Wang, Yafei Gao, Li Xu, Xukai Jiang, Min Xiao   +7 more
doaj   +1 more source

Donor‐Substituted C(sp3)‐Bridged Phosphorus‐Heterotriangulenes as Blue Thermally Activated Delayed Fluorescence Emitters

Advanced Optical Materials, EarlyView.
The newly developed regioselective strategy for the para‐functionalization of C(sp3)‐bridged phosphorus‐centered heterotriangulene delivers a series of donor‐acceptor emitters exhibiting thermally activated delayed fluorescence. The carbazole‐substituted compounds feature a unique combination of high photoluminescence quantum yields up to 75%, deep ...
Maximilian Schöner, Angelina Jocic, Siegfried Harrer, Mahni Fatahi, Jonas Maurmann, Andrea Reule, Frank Rominger, Eli Zysman‐Colman, Milan Kivala   +8 more
wiley   +1 more source

Stable BF2 Boracycles as Versatile Reagents for Selective Ortho C–H Functionalization

Angewandte Chemie, EarlyView.
We report a robust, metal‐free and scalable synthesis of stable BF2 boracycles via directed ortho CH borylation, delivering isolable, shelf‐stable reagents without chromatographic purification. These BF2 boracycles exhibit unique and tunable reactivity, enabling highly selective ipso‐functionalization across a broad range of transformations.
Ganesh H. Shinde, Jonatan Babiker, Michelle Mebrahtu, Anaïs Prigent, Gauthier Foucras, Yogesh N. Aher, Francoise M. Amombo Noa, Magnus J. Johansson, Janez Košmrlj, Ross D. Jansen‐van Vuuren, Thomas Cailly, Henrik Sundén   +11 more
wiley   +2 more sources