Results 41 to 50 of about 748,093 (313)

The Belgian Virtual Tumorbank: A Tool for Translational Cancer Research

Frontiers in Medicine, 2019
Background: Biobanks play a critical role in cancer research by providing high quality biological samples for research. However, the availability of tumor samples in single research institutions is often limited, especially for rare cancers.
Kim Vande Loock, Eva Van der Stock, Annelies Debucquoy, Katia Emmerechts, Nancy Van Damme, Etienne Marbaix   +5 more
doaj   +1 more source

The relative risk of second primary cancers in Switzerland: a population-based retrospective cohort study

BMC Cancer, 2020
Background More people than ever before are currently living with a diagnosis of cancer and the number of people concerned is likely to continue to rise. Cancer survivors are at risk of developing a second primary cancer (SPC).
Anita Feller, Katarina L. Matthes, Andrea Bordoni, Christine Bouchardy, Jean-Luc Bulliard, Christian Herrmann, Isabelle Konzelmann, Manuela Maspoli, Mohsen Mousavi, Sabine Rohrmann, Katharina Staehelin, Volker Arndt, the NICER Working Group   +12 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

SPATIAL DATA WEB SERVICES PRICING MODEL INFRASTRUCTURE [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2013
The General Directorate of Land Registry and Cadastre (TKGM) which is the leader in the field of cartography largely continues its missions which are; to keep and update land registry and cadastre system of the country under the responsibility of the ...
L. Ozmus, B. Erkek, S. Colak, I. Cankurt, S. Bakıcı   +4 more
doaj   +1 more source

The Danish Schizophrenia Registry [PDF]

Clinical Epidemiology, 2016
To systematically monitor and improve the quality of treatment and care of patients with schizophrenia in Denmark. In addition, the database is accessible as a resource for research.Patients diagnosed with schizophrenia and receiving mental health care in psychiatric hospitals or outpatient clinics.
Baandrup, Lone, Cerqueira, Charlotte, Haller, Lea, Korshoej, Lene, Voldsgaard, Inge, Nordentoft, Merete   +5 more
openaire   +7 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Cost-effectiveness of expanding the target population of biennial screening for breast cancer from ages 50–69 to 45 and/or 74: A cohort modelling study in the Finnish setting

Health Economics Review
Background Within Finland’s breast cancer screening program, all women aged 50–69 are invited to biennial screening. Current European guidelines recommend screening in ages 45–49 and 70–74 conditional upon, inter alia, demonstrated context-specific cost ...
Filip Siegfrids, Sirpa Heinävaara, Tytti Sarkeala, Laura Niinikoski, Juha Laine   +4 more
doaj   +1 more source

Evaluating incidence and mortality trends of early-onset colorectal cancer and adenoma in Belgium

ESMO Gastrointestinal Oncology
Background: Colorectal cancer (CRC) incidence is rising among young adults globally, yet European data remain inconclusive. This study evaluated age- and sex-specific trends in CRC incidence, adenoma detection, and mortality in Belgium, with a focus on ...
S. Janssens, K. Van Herck, J. Francart, B. Van Gool, A. Audibert, C. Clinckaert, N. Van Damme, K. Haustermans, L. Van Eycken   +8 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Registrations in the AEA RCT Registry (2013-05-15 through 2021-07-31)

This dataset contains publicly available data on the American Economic Association's RCT registry downloaded August 5 ...
AEA RCT Registry
core   +1 more source