Results 71 to 80 of about 107,019 (266)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

On the Structures of Abelian π-Regular Rings

International Journal of Mathematics and Mathematical Sciences, 2014
Assume that R is an Abelian ring. In this paper, we characterize the structure of R whenever R is π-regular. It is also proved that an Abelian π-regular ring is isomorphic to the subdirect sum of some metadivision rings.
Jianwei Lu, Liguo He
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Simple modules over Auslander regular rings

Open Mathematics, 2017
In this paper, we discuss the properties of simple modules over Auslander regular rings with global dimension at most 3. Using grade theory, we show the right projective dimension of ExtΛ1(S,Λ)$\begin{array}{} \text{Ext}_{{\it\Lambda}}^{1}(S,\ {\it ...
Huang Chonghui, Zheng Lijing
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Neutrosophic Regular Rings and Properties of Their Ideals [PDF]

Neutrosophic Sets and Systems
The goal of the research is to discover the required and sufficient conditions for 𝑅(𝐼) to be a neutrosophic regular as well as the properties of the neutrosophic ideals in the neutrosophic regular ring.
Murhaf Riad Alabdullah
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

On SF-rings and Regular Rings

Kyungpook mathematical journal, 2013
Abstract. A ring R is called a left (right) SF-ring if simple left (right) R-modules areflat. It is still unknown whether a left (right) SF-ring is von Neumann regular. In thispaper, we give some conditions for a left (right) SF-ring to be (a) von Neumann regular;(b) strongly regular; (c) division ring.
Tikaram Subedi, Ardeline Mary Buhphang
openaire   +2 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

The Structure of Regular in Symbolic 2-Plithogenic Rings and the Most Important Properties of Their Elements

Journal of Mathematics
In this paper, we generalize the regularity to a symbolic 2-plithogenic structure. We present the structure and elementary properties of regular symbolic 2-plithogenic rings. We also found that the classical regular ring R is equivalent to the symbolic 2-
Murhaf Riad Alabdullah
doaj   +1 more source