Results 81 to 90 of about 110,346 (305)
Strongly Involution k-regular nil clean ring
NTU Journal of Pure SciencesThis article is about A-rings R, for which every element is a sum of an involution k-regular element and a nilpotent element, which commute with each other. These rings are called strongly involution k-regular nil-clean rings or SIKRNC rings.
Ali Shakir Mahmood +1 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
𝐾₁ of a commutative von Neumann regular ring [PDF]
, 1972 Let A be a commutative regular ring (in the sense of von Neumann), and let q be an ideal in A. Then K 1 ( A , q ) = U ( A , q
Leslie G. Roberts
core +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Valuations determined by quadratic transforms of a regular ring [PDF]
, 2004 Let R be a regular noetherian local ring and let V be the ring of a zero-dimensional valuation v of the quotient field of R dominating R. The aim of this paper is to characterize when V can be obtained from R by the sequence of successive quadratic ...
Granja, A.
core +1 more source
ON Locally Semi Right Invo-Regular Ring
NTU Journal of Pure SciencesAn associative ?i?g ???? with identity is claimed to be locally ????i?ht (le?t) semi invo-Reg. Ring (L.S.I.Reg.Ri?g) , if for every elemen? a in ???? , either a or (1 ? a) is ????ight (le?t) semi involution Reg. elemen?
Yasmine Al Younis, Zubaida Ibraheem
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
A constrained vortex model with relevance to helicopter vortex ring state [PDF]
, 2005 A planar model of a lifting surface descending into its own wake is constructed with the aim of demonstrating some underlying mechanisms of the ‘vortex ring’ state that may be enteredby a rotary wing aircraft during a vertical descent.
Sandham, N.D.
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source