Results 61 to 70 of about 392,803 (276)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

On regular local rings [PDF]

open access: yesProceedings of the American Mathematical Society, 1963
This paper generalizes slightly a result of Kunz [1 ] and Nakai [2]. If R> S are commutative rings with identity we introduce a module D*(R/S) defined as the quotient of the module D(R/S) of S differentials of R by the submodule consisting of elements which are mapped to zero by every homomorphism of D(R/S) having values in a finitely generated R ...
openaire   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

On Strongly - Regular Rings

open access: yesمجلة ابحاث كلية التربية الاساسية
             In our study we examine  definition of strongly γ -regular rings and associates, investigate  interplay between strongly γ - regular rings and other reduced rings. We also study GP – injective modules, and discuss its relation with strongly
Luma Ahmed Khaleel, Beyda S. Abdullah
doaj   +1 more source

Strongly Semiunits and Tri-Regular Elements in Rings [PDF]

open access: yesEurasian Journal of Science and Engineering, 2018
In this paper we study semiunit elements in the group ring Z2G, where G is a cyclic group and we introduce and discuss strongly semiunit elements in Zn, for n=p, 2p, p2 where p is an odd prime.
Parween Ali Hummadi , Suham Hamad Awla
doaj   +1 more source

Non-commutative Regular Rings

open access: yesJournal of Algebra, 2001
In a previous article, the author introduced a noncommutative concept of Cohen-Macaulay ring based on invertible ideals rather than invertible elements [J. Algebra 236, No. 2, 522-548 (2001; Zbl 0982.16008)]; here he narrows the focus to a corresponding notion of regular (semi)local ring.
openaire   +1 more source

Flat Regular Quotient Rings [PDF]

open access: yesTransactions of the American Mathematical Society, 1969
0. Introduction and notation. In this paper we study the condition that the maximal right quotient (MRQ) ring Q [10, p. 106] of a right nonsingular ring R with 1 is flat as a left R-module. It is known [11, p. 134] that if Q is the classical right quotient ring of R, then Q is flat as a left R-module. This is not always the case with the MRQ ring of R:
openaire   +2 more sources

GENERALIZING $\pi$-REGULAR RINGS

open access: yesTaiwanese Journal of Mathematics, 2015
to appear in Taiwanese J ...
Danchev, Peter, Šter, Janez
openaire   +3 more sources

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